| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3879633 | F | Cytotoxicity against AGT-positive human SF763 cells assessed as reduction in cell viability measured after 24 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA3879634 | F | Potency index, ratio of ACNU IC50 to test compound IC50 for AGT-positive human SF763 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA3879635 | F | Cytotoxicity against AGT-positive human SF763 cells assessed as reduction in cell viability pretreated with O6-BG for 2 hrs followed by addition of compound measured after 24 hrs by CCK8 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA3879636 | F | Potency index, ratio of ACNU IC50 in combination with O6-BG to test compound IC50 for AGT-positive human SF763 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA3879637 | F | Potency index, ratio of BCNU IC50 to test compound IC50 for AGT-positive human SF763 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3879638 | F | Potency index, ratio of BCNU IC50 in combination with O6-BG to test compound IC50 for AGT-positive human SF763 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3879639 | F | Cytotoxicity against AGT-positive human SF767 cells assessed as reduction in cell viability measured after 24 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA3879641 | F | Cytotoxicity against AGT-deficient human SF126 cells assessed as reduction in cell viability measured after 24 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA3879642 | F | Potency index, ratio of ACNU IC50 to test compound IC50 for AGT-deficient human SF126 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3879644 | B | Inhibition of AGT in human SF763 cells assessed as increase in dG-dC crosslinking incubated for 12 hrs by HPLC-ESI-MS/MS analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA3879645 | B | Inhibition of AGT in human SF767 cells assessed as increase in dG-dC crosslinking incubated for 12 hrs by HPLC-ESI-MS/MS analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA3879646 | B | Binding affinity to DNA in AGT-deficient human SF126 cells assessed as increase in dG-dC crosslinking incubated for 12 hrs by HPLC-ESI-MS/MS analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA3879647 | B | Binding affinity to calf thymus DNA assessed as increase in dG-dC crosslinking incubated for 12 hrs under dark condition by HPLC-ESI-MS/MS analysis | Bos taurus | 3 | assay format | Scientific Literature | ||
| 14. | ALA3879648 | B | Inhibition of AGT in human SF763 cells assessed as increase in dG-dC crosslinking at 0.1 mM incubated for 12 hrs by HPLC-ESI-MS/MS analysis relative to BCNU | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3879649 | B | Inhibition of AGT in human SF763 cells assessed as increase in dG-dC crosslinking at 0.2 mM incubated for 12 hrs by HPLC-ESI-MS/MS analysis relative to BCNU | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3879650 | B | Inhibition of AGT in human SF763 cells assessed as increase in dG-dC crosslinking at 0.4 mM incubated for 12 hrs by HPLC-ESI-MS/MS analysis relative to BCNU | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3879651 | B | Inhibition of AGT in human SF763 cells assessed as increase in dG-dC crosslinking at 0.6 mM incubated for 12 hrs by HPLC-ESI-MS/MS analysis relative to BCNU | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3879652 | B | Inhibition of AGT in human SF763 cells assessed as increase in dG-dC crosslinking at 0.1 mM incubated for 12 hrs by HPLC-ESI-MS/MS analysis relative to ACNU | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3879653 | B | Inhibition of AGT in human SF763 cells assessed as increase in dG-dC crosslinking at 0.2 mM incubated for 12 hrs by HPLC-ESI-MS/MS analysis relative to ACNU | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3879654 | B | Inhibition of AGT in human SF763 cells assessed as increase in dG-dC crosslinking at 0.4 mM incubated for 12 hrs by HPLC-ESI-MS/MS analysis relative to ACNU | Homo sapiens | 1 | cell-based format | Scientific Literature |
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