# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3877543 | B | Agonist activity at human (alpha4beta2 )2beta2 expressed in human SH-EP1 cells after 9.5 mins by 86Rb+ efflux assay relative to carbamylcholine | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
2. | ALA3877544 | B | Displacement of [3H]epibatidine from rat alpha2beta2 nAChR by liquid scintillation counting | Rattus norvegicus | 9 | protein complex format | Scientific Literature | ||
3. | ALA3877546 | B | Displacement of [3H]epibatidine from rat alpha3beta2 nAChR by liquid scintillation counting | Rattus norvegicus | 9 | protein complex format | Scientific Literature | ||
4. | ALA3877548 | B | Displacement of [3H]epibatidine from rat alpha4beta2 nAChR by liquid scintillation counting | Rattus norvegicus | 9 | protein complex format | Scientific Literature | ||
5. | ALA3877549 | B | Displacement of [3H]epibatidine from rat forebrain alpha4beta2* nAChR by liquid scintillation counting | Rattus norvegicus | 9 | assay format | Scientific Literature | ||
6. | ALA3877550 | B | Displacement of [3H]epibatidine from rat alpha4beta4 nAChR by liquid scintillation counting | Rattus norvegicus | 9 | protein complex format | Scientific Literature | ||
7. | ALA3877551 | B | Displacement of [3H]epibatidine from rat forebrain alpha7* nAChR at 10 uM by liquid scintillation counting | Rattus norvegicus | 9 | assay format | Scientific Literature | ||
8. | ALA3877552 | B | Agonist activity at human alpha4beta2 nAChR expressed in human SH-EP1 cells after 9.5 mins by 86Rb+ efflux assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
9. | ALA3877553 | B | Antagonist activity at human alpha4beta2 expressed in human SH-EP1 cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated for 10 mins followed by carbamylcholine addition measured after 5 mins by Cherenkov counting | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
10. | ALA3877556 | B | Agonist activity at human (alpha4beta2 )2alpha4 expressed in human SH-EP1 cells after 9.5 mins by 86Rb+ efflux assay relative to carbamylcholine | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
11. | ALA3877557 | B | Displacement of [3H]epibatidine from rat alpha7 nAChR at 10 uM by liquid scintillation counting | Rattus norvegicus | 9 | single protein format | Scientific Literature | ||
12. | ALA3877558 | A | Displacement of [3H]epibatidine from rat alpha3beta4 nAChR at 10 uM by liquid scintillation counting | Rattus norvegicus | 4 | protein complex format | Scientific Literature | ||
13. | ALA3877559 | B | Displacement of [3H]epibatidine from rat alpha2beta4 nAChR at 10 uM by liquid scintillation counting | Rattus norvegicus | 2 | protein complex format | Scientific Literature | ||
14. | ALA3877562 | A | Agonist activity at alpha3beta4* nAChR in human SH-SY5Y cells after 9.5 mins by 86Rb+ efflux assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
15. | ALA3877563 | A | Antagonist activity at alpha3beta4* in human SH-SY5Y cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated for 10 mins followed by carbamylcholine addition measured after 5 mins by Cherenkov counting | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
16. | ALA3877564 | B | Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
17. | ALA3877565 | B | Antagonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated for 10 mins followed by carbamylcholine addition measured after 5 mins by Cherenkov counting | Homo sapiens | 7 | cell-based format | Scientific Literature |