# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3859037 | Binding | Inhibition of human PRMT1 assessed as inhibition of methylation activity using biotin-labeled peptide as substrate and [3H]-SAM by scintillation proximity assay | Homo sapiens | 1 | ALA3856251 | single protein format | Scientific Literature | |
2. | ALA3859038 | Binding | Inhibition of human PRMT3 assessed as inhibition of methylation activity using biotin-labeled peptide as substrate and [3H]-SAM by scintillation proximity assay | Homo sapiens | 1 | ALA3856251 | single protein format | Scientific Literature | |
3. | ALA3859039 | Binding | Inhibition of human PRMT4 assessed as inhibition of methylation activity using biotin-labeled peptide as substrate and [3H]-SAM by scintillation proximity assay | Homo sapiens | 1 | ALA3856251 | single protein format | Scientific Literature | |
4. | ALA3859040 | Binding | Inhibition of human PRMT6 assessed as inhibition of methylation activity using biotin-labeled peptide as substrate and [3H]-SAM by scintillation proximity assay | Homo sapiens | 1 | ALA3856251 | single protein format | Scientific Literature | |
5. | ALA3859041 | Binding | Inhibition of human PRMT8 assessed as inhibition of methylation activity using biotin-labeled peptide as substrate and [3H]-SAM by scintillation proximity assay | Homo sapiens | 1 | ALA3856251 | single protein format | Scientific Literature | |
6. | ALA4346577 | Binding | Inhibition of type 1 PRMT (unknown origin) | Homo sapiens | 1 | ALA4342528 | assay format | Scientific Literature | |
7. | ALA4346598 | Binding | Inhibition of Flag-tagged PRMT6 (unknown origin) expressed in HEK293 cells at 2 uM incubated for 20 hrs assessed as reduction in H3R2me2a levels | Homo sapiens | 1 | ALA4342528 | cell-based format | Scientific Literature | |
8. | ALA4398123 | Binding | Inhibition of PRMT1 (unknown origin) using biotinylated histone H4 (1 to 24 residues) as substrate in presence of [3H]SAM by scintillation proximity assay | Homo sapiens | 1 | ALA4396888 | single protein format | Scientific Literature | |
9. | ALA4398124 | Binding | Inhibition of PRMT3 (unknown origin) using biotinylated histone H4 (1 to 24 residues) as substrate in presence of [3H]SAM by scintillation proximity assay | Homo sapiens | 1 | ALA4396888 | single protein format | Scientific Literature | |
10. | ALA4398125 | Binding | Inhibition of PRMT4 (unknown origin) using biotinylated histone H4 (1 to 24 residues) as substrate in presence of [3H]SAM by scintillation proximity assay | Homo sapiens | 1 | ALA4396888 | single protein format | Scientific Literature | |
11. | ALA4398126 | Binding | Inhibition of PRMT6 (unknown origin) using biotinylated histone H4 (1 to 24 residues) as substrate in presence of [3H]SAM by scintillation proximity assay | Homo sapiens | 1 | ALA4396888 | single protein format | Scientific Literature | |
12. | ALA4398127 | Binding | Inhibition of PRMT8 (unknown origin) using biotinylated histone H4 (1 to 24 residues) as substrate in presence of [3H]SAM by scintillation proximity assay | Homo sapiens | 1 | ALA4396888 | single protein format | Scientific Literature | |
13. | ALA4495582 | Functional | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
14. | ALA4513082 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
15. | ALA4725212 | Toxicity | Incucyte cell viability with HEK293T | Homo sapiens | 1,713 | ALA4689842 | cell-based format | EUbOPEN Chemogenomic Library | |
16. | ALA4725213 | Toxicity | Incucyte cell viability with human fibroblast | Homo sapiens | 1,718 | ALA4689842 | cell-based format | EUbOPEN Chemogenomic Library | |
17. | ALA4725214 | Toxicity | Incucyte cell viability with U2OS | Homo sapiens | 1,712 | ALA4689842 | cell-based format | EUbOPEN Chemogenomic Library | |
18. | ALA5030834 | Binding | Inhibition of PRMT1 (unknown origin) by scintillation proximity assay | Homo sapiens | 1 | ALA5030506 | single protein format | Scientific Literature | |
19. | ALA5030835 | Binding | Inhibition of PRMT3 (unknown origin) by scintillation proximity assay | Homo sapiens | 1 | ALA5030506 | single protein format | Scientific Literature | |
20. | ALA5030836 | Binding | Inhibition of PRMT4 (unknown origin) by scintillation proximity assay | Homo sapiens | 1 | ALA5030506 | single protein format | Scientific Literature |