# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3880449 | B | Inhibition of pig brain TRH-DE using Glp-His-ProAMC as substrate by DPP-4-based continuous fluorometric method | Sus scrofa | 21 | assay format | Patent Bioactivity Data | ||
2. | ALA3880450 | B | Inhibition of pig brain TRH-DE at 1 uM using Glp-His-ProAMC as substrate by DPP-4-based continuous fluorometric method | Sus scrofa | 1 | assay format | Patent Bioactivity Data | ||
3. | ALA3880452 | F | In vivo inhibition of TRH-DE in cannulated Wistar rat assessed as increase in TRH-mediated wet dog shakes at 5 ug in 1 ul, icv followed by TRH addition measured after 30 mins relative to control | Rattus norvegicus | 1 | organism-based format | Patent Bioactivity Data | ||
4. | ALA3880453 | F | Behavioral effect in cannulated Wistar rat assessed as increase in wet dog shakes at 5 ug in 1 ul, icv after 30 mins | Rattus norvegicus | 2 | assay format | Patent Bioactivity Data | ||
5. | ALA3880456 | F | In vivo inhibition of TRH-DE in cannulated Wistar rat assessed as increase in TRH-mediated grooming at 10 mg/kg, ip measured every 5 mins for 30 secs during 40 mins observation period | Rattus norvegicus | 1 | organism-based format | Patent Bioactivity Data | ||
6. | ALA3880457 | F | In vivo inhibition of TRH-DE in cannulated Wistar rat assessed as increase in TRH-mediated sniffing at 10 mg/kg, ip measured every 5 mins for 30 secs during 40 mins observation period | Rattus norvegicus | 1 | organism-based format | Patent Bioactivity Data | ||
7. | ALA3880458 | F | In vivo inhibition of TRH-DE in cannulated Wistar rat assessed as increase in TRH-mediated chewing at 10 mg/kg, ip measured every 5 mins for 30 secs during 40 mins observation period | Rattus norvegicus | 1 | organism-based format | Patent Bioactivity Data | ||
8. | ALA3880462 | F | In vivo inhibition of TRH-DE in cannulated Wistar rat assessed as increase in TRH-mediated wet dog shakes at 10 mg/kg, ip measured for last 25 mins of the 40 mins observation period | Rattus norvegicus | 1 | organism-based format | Patent Bioactivity Data | ||
9. | ALA3880464 | B | Displacement of [3H]-3MeHis-TRH from TRH receptor in Sprague-Dawley rat cortical membranes | Rattus norvegicus | 3 | assay format | Patent Bioactivity Data | ||
10. | ALA3880469 | B | Reversible inhibition of pig brain TRH-DE using Glp-His-ProAMC as substrate at 1 uM preincubated for 75 mins by by DPP-4-based continuous fluorometric method | Sus scrofa | 1 | assay format | Patent Bioactivity Data | ||
11. | ALA3880472 | B | Time-dependent inhibition of pig brain TRH-DE using Glp-His-ProAMC as substrate at 1 uM preincubated for 75 mins by DPP-4-based continuous fluorometric method | Sus scrofa | 1 | assay format | Patent Bioactivity Data |