| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3868397 | B | Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric method | Homo sapiens | 21 | single protein format | Scientific Literature | ||
| 2. | ALA3868399 | B | Inhibition of recombinant human AMPA-activated MMP2 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric method | Homo sapiens | 21 | single protein format | Scientific Literature | ||
| 3. | ALA3868402 | B | Inhibition of recombinant human AMPA-activated MMP8 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric method | Homo sapiens | 21 | single protein format | Scientific Literature | ||
| 4. | ALA3868404 | B | Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric method | Homo sapiens | 21 | single protein format | Scientific Literature | ||
| 5. | ALA3868408 | P | Solubility of the compound at pH 6.8 | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA3868409 | A | Permeability of the compound at pH 7.4 by PAMPA assay | 3 | assay format | Scientific Literature | |||
| 7. | ALA3868410 | A | Clearance in human liver microsomes | Homo sapiens | 3 | tissue-based format | Scientific Literature | ||
| 8. | ALA3868411 | A | Clearance in rat liver microsomes | Rattus norvegicus | 3 | tissue-based format | Scientific Literature | ||
| 9. | ALA3868412 | A | Volume of distribution in rat at 0.1 mg/kg, iv or 1 mg/kg, po | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA3868413 | A | Clearance in rat at 0.1 mg/kg, iv or 1 mg/kg, po | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 11. | ALA3868414 | A | Oral bioavailability in rat at 1 mg/kg | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 12. | ALA3868415 | A | Inhibition of CYP3A4 (unknown origin) at 10 uM | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 13. | ALA3868416 | U | Selectivity ratio of IC50 for recombinant human AMPA-activated MMP1 to IC50 recombinant human AMPA-activated MMP13 | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 14. | ALA3868417 | B | Selectivity ratio of IC50 for recombinant human AMPA-activated MMP2 to IC50 recombinant human AMPA-activated MMP13 | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 15. | ALA3868418 | B | Selectivity ratio of IC50 for recombinant human AMPA-activated MMP3 to IC50 recombinant human AMPA-activated MMP13 | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 16. | ALA3868419 | B | Selectivity ratio of IC50 for recombinant human AMPA-activated MMP7 to IC50 recombinant human AMPA-activated MMP13 | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 17. | ALA3868420 | B | Selectivity ratio of IC50 for recombinant human AMPA-activated MMP8 to IC50 recombinant human AMPA-activated MMP13 | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 18. | ALA3868421 | B | Selectivity ratio of IC50 for recombinant human AMPA-activated MMP9 to IC50 recombinant human AMPA-activated MMP13 | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 19. | ALA3868422 | B | Selectivity ratio of IC50 for recombinant human AMPA-activated MMP10 to IC50 recombinant human AMPA-activated MMP13 | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 20. | ALA3868423 | B | Selectivity ratio of IC50 for recombinant human AMPA-activated MMP12 to IC50 recombinant human AMPA-activated MMP13 | Homo sapiens | 3 | assay format | Scientific Literature |
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