# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3859786 | Binding | Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay | Homo sapiens | 22 | ALA3856283 | single protein format | Scientific Literature | |
2. | ALA3859787 | Binding | Inhibition of recombinant MLL1 (unknown origin) interaction with recombinant ASH2L/RBBP5/WDR5 (unknown origin) assessed as decrease in histone methylation after 60 mins by Alpha Screen assay | Homo sapiens | 3 | ALA3856283 | protein complex format | Scientific Literature | |
3. | ALA3859788 | Functional | Antiproliferative activity against human MV4-11 cells harboring MLL-AF4 assessed as inhibition of cell viability after 72 hrs by CCK8-based colorimetric assay | Homo sapiens | 13 | ALA3856283 | cell-based format | Scientific Literature | |
4. | ALA3859789 | Functional | Antiproliferative activity against human K562 cells harboring BCR-ABL assessed as inhibition of cell viability after 72 hrs by CCK8-based colorimetric assay | Homo sapiens | 13 | ALA3856283 | cell-based format | Scientific Literature | |
5. | ALA3859791 | ADME | Permeability of the compound after 4 hrs by PAMPA | 15 | ALA3856283 | assay format | Scientific Literature |