# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA655956 | B | Binding affinity against C167A human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand; UB is Undetectable Binding | 1 | single protein format | Scientific Literature | |||
2. | ALA658304 | F | Compound was evaluated for the inhibition of IPs hydrolysis on intact CHO cells expressing the human tachykinin NK-1 receptor | Cricetulus griseus | 3 | cell-based format | Scientific Literature | ||
3. | ALA658305 | F | Compound was evaluated for the inhibition of cAMP formation on intact CHO cells expressing the human tachykinin NK-1 receptor | Cricetulus griseus | 3 | cell-based format | Scientific Literature | ||
4. | ALA677164 | B | Binding affinity against F112A human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand | 1 | single protein format | Scientific Literature | |||
5. | ALA678315 | B | Binding affinity against F168A human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand | 1 | single protein format | Scientific Literature | |||
6. | ALA679210 | B | Binding affinity against F293A human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand | 1 | single protein format | Scientific Literature | |||
7. | ALA880092 | F | Compound was evaluated for K+ release in SP-P system and relative potency was determined against Guinea pig ileum | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
8. | ALA683331 | F | Compound was evaluated for potency relative to neurokinin B against SP-N system (enteric nerves of Guinea pig ileum) | Cavia porcellus | 4 | organism-based format | Scientific Literature | ||
9. | ALA689855 | B | Binding affinity against H198A human neurokinin-2 receptor (hNK-2R) using [125I]-NKA as a radioligand; UB is Undetectable Binding | 1 | single protein format | Scientific Literature | |||
10. | ALA689894 | F | Compound was evaluated for potency in SP-E system and relative potency was determined against Hamster urinary bladder | Cricetulus griseus | 4 | organism-based format | Scientific Literature | ||
11. | ALA702053 | B | Binding affinity against I202F human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand | 1 | single protein format | Scientific Literature | |||
12. | ALA740710 | F | Determination of serum specificity with immunogen 1-MBSA in ELISA against the respective tachykinins of mice; - indicates Nondetectable interaction | Mus musculus | 1 | organism-based format | Scientific Literature | ||
13. | ALA740712 | F | Determination of serum specificity with immunogen 2-MBSA in ELISA against the respective tachykinins of mice; +++ indicates Strong recognition | Mus musculus | 1 | organism-based format | Scientific Literature | ||
14. | ALA879298 | F | Determination of serum specificity with immunogen 3-MBSA in ELISA against the respective tachykinins of mice; - indicates Nondetectable interaction | Mus musculus | 2 | organism-based format | Scientific Literature | ||
15. | ALA750371 | B | Binding affinity against N110A human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand; UB is Undetectable Binding | 1 | single protein format | Scientific Literature | |||
16. | ALA745326 | B | Evaluated for the binding affinity against NK2 receptor | Cavia porcellus | 1 | single protein format | Scientific Literature | ||
17. | ALA744867 | F | Tested for the binding affinity to human NK2 receptor expressed in Sf-9 insect larval cells using 0.1 nM 2-[125 I] iodohistidyl neurokinin A | 3 | cell-based format | Scientific Literature | |||
18. | ALA751783 | B | Compound was evaluated for affinity towards human tachykinin NK-1 receptor expressed in CHO cells | 7 | cell-based format | Scientific Literature | |||
19. | ALA750065 | F | Compound was evaluated for concentration-dependent and oscillatory increase in [Ca2+], caused by activation of hNK3 receptors in CHO cells | 4 | cell-based format | Scientific Literature | |||
20. | ALA750067 | B | Compound was evaluated for its ability to displace [3H]NKB binding in hNK3 receptors expressed in CHO cells | 4 | cell-based format | Scientific Literature |