# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA655956 | Binding | Binding affinity against C167A human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand; UB is Undetectable Binding | 1 | ALA1135528 | single protein format | Scientific Literature | ||
2. | ALA658304 | Functional | Compound was evaluated for the inhibition of IPs hydrolysis on intact CHO cells expressing the human tachykinin NK-1 receptor | Cricetulus griseus | 3 | ALA1130821 | cell-based format | Scientific Literature | |
3. | ALA658305 | Functional | Compound was evaluated for the inhibition of cAMP formation on intact CHO cells expressing the human tachykinin NK-1 receptor | Cricetulus griseus | 3 | ALA1130821 | cell-based format | Scientific Literature | |
4. | ALA677164 | Binding | Binding affinity against F112A human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand | 1 | ALA1135528 | single protein format | Scientific Literature | ||
5. | ALA678315 | Binding | Binding affinity against F168A human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand | 1 | ALA1135528 | single protein format | Scientific Literature | ||
6. | ALA679210 | Binding | Binding affinity against F293A human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand | 1 | ALA1135528 | single protein format | Scientific Literature | ||
7. | ALA880092 | Functional | Compound was evaluated for K+ release in SP-P system and relative potency was determined against Guinea pig ileum | Cavia porcellus | 3 | ALA1123317 | organism-based format | Scientific Literature | |
8. | ALA683331 | Functional | Compound was evaluated for potency relative to neurokinin B against SP-N system (enteric nerves of Guinea pig ileum) | Cavia porcellus | 4 | ALA1123317 | organism-based format | Scientific Literature | |
9. | ALA689855 | Binding | Binding affinity against H198A human neurokinin-2 receptor (hNK-2R) using [125I]-NKA as a radioligand; UB is Undetectable Binding | 1 | ALA1135528 | single protein format | Scientific Literature | ||
10. | ALA689894 | Functional | Compound was evaluated for potency in SP-E system and relative potency was determined against Hamster urinary bladder | Cricetulus griseus | 4 | ALA1123317 | organism-based format | Scientific Literature | |
11. | ALA702053 | Binding | Binding affinity against I202F human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand | 1 | ALA1135528 | single protein format | Scientific Literature | ||
12. | ALA821390 | Binding | Binding affinity against wild type human Wild-type tachykinin receptor 2 (hNK-2R) using [125I]NKA as a radioligand | 1 | ALA1135528 | single protein format | Scientific Literature | ||
13. | ALA824195 | Binding | Binding affinity against Y107A human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand | 1 | ALA1135528 | single protein format | Scientific Literature | ||
14. | ALA824198 | Binding | Binding affinity against Y169A human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand; UB is Undetectable Binding | 1 | ALA1135528 | single protein format | Scientific Literature | ||
15. | ALA824201 | Binding | Binding affinity against Y206F human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand | 1 | ALA1135528 | single protein format | Scientific Literature | ||
16. | ALA881673 | Binding | Binding affinity against Y266F human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand | 3 | ALA1135528 | single protein format | Scientific Literature | ||
17. | ALA824206 | Binding | Binding affinity against Y269A human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand; UB is Undetectable Binding | 1 | ALA1135528 | single protein format | Scientific Literature | ||
18. | ALA824207 | Binding | Binding affinity against Y269F human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand | 1 | ALA1135528 | single protein format | Scientific Literature | ||
19. | ALA824209 | Binding | Binding affinity against Y289F human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand | 1 | ALA1135528 | single protein format | Scientific Literature | ||
20. | ALA824731 | Binding | Binding affinity against Y289T human neurokinin-2 receptor (hNK-2R) using [125I]NKA as a radioligand; UB is Undetectable Binding | 1 | ALA1135528 | single protein format | Scientific Literature |