# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3880815 | B | Activation of RARalpha (unknown origin) expressed in human HeLa cells co-expressing ERE-beta-Glob-Luc-SV-Neo incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 18 | ALA3880406 | cell-based format | Patent Bioactivity Data | |
2. | ALA3880816 | B | Activation of RARbeta (unknown origin) expressed in human HeLa cells co-expressing ERE-beta-Glob-Luc-SV-Neo incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 18 | ALA3880406 | cell-based format | Patent Bioactivity Data | |
3. | ALA3880817 | B | Activation of RARgamma (unknown origin) expressed in human HeLa cells co-expressing ERE-beta-Glob-Luc-SV-Neo incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 18 | ALA3880406 | cell-based format | Patent Bioactivity Data | |
4. | ALA4195063 | B | Agonist activity at GAL4 DNA-binding domain-tagged RARgamma (unknown origin) ligand-binding domain expressed in human HG5LN cells incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 32 | ALA4190387 | cell-based format | Scientific Literature | |
5. | ALA4195064 | A | Agonist activity at GAL4 DNA-binding domain-tagged RARalpha (unknown origin) ligand-binding domain expressed in human HG5LN cells incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 25 | ALA4190387 | cell-based format | Scientific Literature | |
6. | ALA4195065 | B | Selectivity index, ratio of EC50 for GAL4 DNA-binding domain-tagged RARalpha (unknown origin) ligand-binding domain expressed in human HG5LN cells to EC50 for GAL4 DNA-binding domain-tagged RARgamma (unknown origin) ligand-binding domain expressed in human HG5LN cells | Homo sapiens | 22 | ALA4190387 | cell-based format | Scientific Literature | |
7. | ALA4195066 | B | Agonist activity at GAL4 DNA-binding domain-tagged RARbeta (unknown origin) ligand-binding domain expressed in human HG5LN cells incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 23 | ALA4190387 | cell-based format | Scientific Literature | |
8. | ALA4195067 | B | Selectivity index, ratio of EC50 for GAL4 DNA-binding domain-tagged RARbeta (unknown origin) ligand-binding domain expressed in human HG5LN cells to EC50 for GAL4 DNA-binding domain-tagged RARgamma (unknown origin) ligand-binding domain expressed in human HG5LN cells | Homo sapiens | 22 | ALA4190387 | cell-based format | Scientific Literature | |
9. | ALA4195068 | A | Intrinsic clearance in cryopreserved human hepatocytes assessed per million cells at 1 uM incubated up to 90 mins by LC-MS/MS method | Homo sapiens | 14 | ALA4190387 | cell-based format | Scientific Literature | |
10. | ALA4195069 | P | Chromatographic hydrophobicity index, log D of the compound at pH 6.5 by HPLC method | 13 | ALA4190387 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA4195070 | A | Unbound fraction in plasma (unknown origin) | Not specified | 34 | ALA4190387 | cell-free format | Scientific Literature |