| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3858503 | B | Inhibition of human mPGES-1 expressed in 293E cells assessed as reduction in conversion of PGH2 to PGE2 after 1.5 min by LC/MS analysis | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 2. | ALA3858504 | B | Inhibition of mPGES-1 in human A549 cells assessed as reduction in recombinant human interleukin-1 beta-induced PGE2 production preincubated for 30 mins measured after 18 hrs by ELISA | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 3. | ALA3858505 | B | Inhibition of mPGES-1 in human whole blood assessed as reduction in LPS-induced PGE2 production preincubated for 30 mins followed by LPS stimulation for 20 to 24 hrs by LC/MS/MS analysis | Homo sapiens | 9 | tissue-based format | Scientific Literature | ||
| 4. | ALA3858507 | A | Inhibition of COX-2 in human A549 cells assessed as reduction in recombinant human interleukin-1 beta-induced PGI2 production up to 10 uM preincubated for 30 mins measured after 18 hrs by ELISA | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 5. | ALA3858508 | B | Inhibition of mPGES-1 in human whole blood assessed as reduction in LPS-induced PGF2alpha production up to 30 uM preincubated for 30 mins followed by LPS stimulation for 20 to 24 hrs by LC/MS/MS analysis | Homo sapiens | 10 | tissue-based format | Scientific Literature | ||
| 6. | ALA3858509 | B | Inhibition of mPGES-1 in human whole blood assessed as reduction in LPS-induced TxB2 production up to 30 uM preincubated for 30 mins followed by LPS stimulation for 20 to 24 hrs by LC/MS/MS analysis | Homo sapiens | 10 | tissue-based format | Scientific Literature | ||
| 7. | ALA3858510 | B | Inhibition of human mPGES-2 | Homo sapiens | 3 | single protein format | Scientific Literature |
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