#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3854930	B	Inhibition of human COT (66 to 395 residues) expressed in Sf21 cells using 5-Fluo-Ahx-AGAGSGQLIDSNleANSFVGTR-NH2 as substrate after 60 mins by caliper microfluidic mobility shift assay	Homo sapiens	25		cell-based format	Scientific Literature
2.	ALA3854931	B	Inhibition of MEK/ERK signaling pathway in TNFalpha-stimulated human A431 cells transfected with COT siRNA assessed as reduction in ERK1/2 phosphorylation incubated for 60 mins followed by stimulation with TNFalpha for 10 mins by Western blot analysis	Homo sapiens	2		cell-based format	Scientific Literature
3.	ALA3854932	B	Inhibition of MEK/ERK signaling pathway in EGF-stimulated human A431 cells transfected with COT siRNA assessed as reduction in ERK1/2 phosphorylation incubated for 60 mins followed by stimulation with EGF for 10 mins by Western blot analysis	Homo sapiens	2		cell-based format	Scientific Literature
4.	ALA3854933	B	Inhibition of COT in LPS-stimulated human PBMC assessed as reduction in ERK1/2 phosphorylation incubated for 60 mins followed by LPS stimulation for 12 mins by flow cytometric analysis	Homo sapiens	8		single protein format	Scientific Literature
5.	ALA3854934	B	Inhibition of COT in LPS-stimulated human PBMC assessed as reduction in TNFalpha release incubated for 1 hr followed by stimulation with LPS for 4 hrs by HTRF assay	Homo sapiens	8		single protein format	Scientific Literature
6.	ALA3854935	B	Inhibition of NFkappaB pathway in LPS-stimulated human PBMC assessed as reduction in p65 phosphorylation incubated for 60 mins followed by LPS stimulation for 12 mins by flow cytometric analysis analysis	Homo sapiens	1		assay format	Scientific Literature
7.	ALA3854936	B	Inhibition of FLT3 (563 to 993 residues) D835Y mutant (unknown origin) after 60 mins in presence of ATP by caliper microfluidic mobility shift assay	Homo sapiens	1		assay format	Scientific Literature
8.	ALA3854937	B	Inhibition of MKNK2 (unknown origin) after 60 mins in presence of ATP by caliper microfluidic mobility shift assay	Homo sapiens	1		single protein format	Scientific Literature
9.	ALA3854938	P	Octanol-water partition coefficient, log P of the compound by shake-flask method		11		small-molecule physicochemical format	Scientific Literature
10.	ALA3854940	B	Inhibition of COT in LPS-stimulated human whole blood assessed as reduction in TNFalpha release incubated for 30 mins followed by stimulation with LPS for 3 hrs by HTRF assay	Homo sapiens	7		tissue-based format	Scientific Literature
11.	ALA3854941	P	Equilibrium solubility of the compound at pH 6.8 after 16 hrs by mass spectrometric analysis		9		small-molecule physicochemical format	Scientific Literature
12.	ALA3854942	P	Equilibrium solubility of the compound at pH 4 after 16 hrs by mass spectrometric analysis		9		small-molecule physicochemical format	Scientific Literature
13.	ALA3854943	A	Protein binding in human plasma at 5 uM after 4 hrs by rapid equilibrium dialysis method	Homo sapiens	6		cell-free format	Scientific Literature