# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA857173 | B | Inhibitory activity against HIV-1 Integrase (HIV-1-IN) | Human immunodeficiency virus 1 | 47 | ALA1135718 | single protein format | Scientific Literature | |
2. | ALA702428 | B | Compound concentration required to reduce HIV-1 Integrase 3'-processing activity by 50% | Human immunodeficiency virus 1 | 26 | ALA1131129 | single protein format | Scientific Literature | |
3. | ALA702983 | F | Compound concentration required to reduce the exponential growth of KB cells by 50% | Homo sapiens | 27 | ALA1131129 | cell-based format | Scientific Literature | |
4. | ALA702437 | F | Fold increase in protein-linked DNA breaks (PLDB) with respect to untreated controls. | Homo sapiens | 27 | ALA1131129 | assay format | Scientific Literature | |
5. | ALA715022 | F | Compound concentration required to reduce the exponential growth of MT-4 cells by 50% | Homo sapiens | 27 | ALA1131129 | cell-based format | Scientific Literature | |
6. | ALA2148249 | A | Cytotoxicity against dog MDCK cells assessed as loss of cell viability incubated for 24 hrs followed by compound wash out measured after 24 hrs by trypan blue exclusion assay | Canis lupus familiaris | 16 | ALA2146419 | cell-based format | Scientific Literature | |
7. | ALA2148250 | A | Cytotoxicity against dog MDCK cells assessed as morphological alterations incubated for 24 hrs followed by compound wash out measured after 24 hrs by microscopic analysis | Canis lupus familiaris | 16 | ALA2146419 | cell-based format | Scientific Literature | |
8. | ALA2148251 | A | Cytotoxicity against dog MDCK cells assessed as modification of cell multiplication rate incubated for 24 hrs followed by compound wash out measured after 24 hrs by cell counting analysis | Canis lupus familiaris | 16 | ALA2146419 | cell-based format | Scientific Literature | |
9. | ALA2148253 | A | Cytotoxicity against dog MDCK cells assessed as morphological alterations at 40 ug/mL incubated for 24 hrs followed by compound wash out measured after 24 hrs by microscopic analysis | Canis lupus familiaris | 3 | ALA2146419 | cell-based format | Scientific Literature | |
10. | ALA2148254 | F | Antiviral activity against Influenza virus A/Puerto Rico/8/34 H1N1 infected in dog MDCK cells incubated at 1 hr post-infection measured after 24 hrs by hemagglutininating unit assay | Influenza A virus | 4 | ALA2146419 | organism-based format | Scientific Literature | |
11. | ALA2148256 | F | Antiviral activity against Influenza virus A/Puerto Rico/8/34 H1N1 infected in dog MDCK cells assessed as inhibition of viral replication at 20 ug/mL incubated at 1 hr post-infection measured after 24 hrs by hemagglutininating unit assay relative to control | Influenza A virus | 2 | ALA2146419 | organism-based format | Scientific Literature | |
12. | ALA2148257 | F | Antiviral activity against Influenza virus A/Puerto Rico/8/34 H1N1 infected in dog MDCK cells incubated for 1 hr prior to infection by hemagglutininating unit assay | Influenza A virus | 2 | ALA2146419 | organism-based format | Scientific Literature | |
13. | ALA2148371 | F | Antiviral activity against Influenza virus A/Puerto Rico/8/34 H1N1 infected in dog MDCK cells incubated for 1 hr post-infection followed by compound washout by hemagglutininating unit assay | Influenza A virus | 2 | ALA2146419 | organism-based format | Scientific Literature | |
14. | ALA2148372 | F | Antiviral activity against Influenza virus A/Puerto Rico/8/34 H1N1 infected in dog MDCK cells incubated overnight prior to infection followed by compound washout by hemagglutininating unit assay | Influenza A virus | 2 | ALA2146419 | organism-based format | Scientific Literature | |
15. | ALA2148373 | F | Antiviral activity against Influenza virus A/Puerto Rico/8/34 H1N1 infected in dog MDCK cells at 20 ug/mL incubated for 2 hrs post-infection followed by compound washout measured after 24 hrs by hemagglutininating unit assay | Influenza A virus | 1 | ALA2146419 | organism-based format | Scientific Literature | |
16. | ALA2148375 | F | Antiviral activity against Influenza virus A/Puerto Rico/8/34 H1N1 infected in dog MDCK cells at 20 ug/mL incubated for 4 hrs post-infection followed by compound washout measured after 24 hrs by hemagglutininating unit assay | Influenza A virus | 1 | ALA2146419 | organism-based format | Scientific Literature | |
17. | ALA2148377 | F | Antiviral activity against Influenza virus A/Puerto Rico/8/34 H1N1 infected in dog MDCK cells at 20 ug/mL incubated for 6 hrs post-infection followed by compound washout measured after 24 hrs by hemagglutininating unit assay relative to control | Influenza A virus | 1 | ALA2146419 | organism-based format | Scientific Literature | |
18. | ALA2148379 | F | Antiviral activity against Influenza virus A/Puerto Rico/8/34 H1N1 infected in dog MDCK cells at 20 ug/mL incubated for 8 hrs post-infection followed by compound washout measured after 24 hrs by hemagglutininating unit assay relative to control | Influenza A virus | 1 | ALA2146419 | organism-based format | Scientific Literature | |
19. | ALA2148828 | F | Antiviral activity against Influenza virus A/Puerto Rico/8/34 H1N1 infected in dog MDCK cells at 20 ug/mL incubated for 24 hrs post-infection followed by compound washout measured after 24 hrs by hemagglutininating unit assay relative to control | Influenza A virus | 1 | ALA2146419 | organism-based format | Scientific Literature | |
20. | ALA2148830 | F | Antiviral activity against Influenza virus A/Puerto Rico/8/34 H1N1 infected in dog MDCK cells incubated at 2 hrs post-infection measured after 24 hrs by hemagglutininating unit assay relative to control | Influenza A virus | 2 | ALA2146419 | organism-based format | Scientific Literature |