# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3877709 | B | Inhibition of mouse GAT1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition measured after 4 mins by liquid scintillation counter method | Mus musculus | 11 | cell-based format | Scientific Literature | ||
2. | ALA3877710 | B | Inhibition of mouse GAT2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition measured after 10 mins by liquid scintillation counter method | Mus musculus | 14 | cell-based format | Scientific Literature | ||
3. | ALA3877711 | B | Inhibition of mouse GAT3 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition measured after 4 mins by liquid scintillation counter method | Mus musculus | 14 | cell-based format | Scientific Literature | ||
4. | ALA3877712 | B | Inhibition of mouse GAT4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition measured after 4 mins by liquid scintillation counter method | Mus musculus | 13 | cell-based format | Scientific Literature | ||
5. | ALA3877724 | B | Selectivity ratio of IC50 for mouse GAT2 expressed in HEK293 cells to IC50 for mouse GAT1 expressed in HEK293 cells | Mus musculus | 1 | cell-based format | Scientific Literature | ||
6. | ALA3877725 | B | Selectivity ratio of IC50 for mouse GAT2 expressed in HEK293 cells to IC50 for mouse GAT3 expressed in HEK293 cells | Mus musculus | 1 | cell-based format | Scientific Literature | ||
7. | ALA3877726 | B | Selectivity ratio of IC50 for mouse GAT2 expressed in HEK293 cells to IC50 for mouse GAT4 expressed in HEK293 cells | Mus musculus | 1 | cell-based format | Scientific Literature |