# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3870595 | Binding | Inhibition of recombinant CETP (unknown origin) assessed as inhibition of BODIPY-labeled cholesteryl transfer to fluorescent substrate by fluorimetric assay | Homo sapiens | 29 | ALA3870315 | single protein format | Scientific Literature | |
2. | ALA3870596 | Functional | In vivo inhibition of CETP in po dosed high-fat fed syrian hamster model assessed as increase in plasma HDL-cholesterol level administered once daily for 5 days measured 2 hrs post last dose | Mesocricetus auratus | 1 | ALA3870315 | organism-based format | Scientific Literature | |
3. | ALA3870597 | ADME | Cmax in Sprague-Dawley rat at 50 mg/Kg, po | Rattus norvegicus | 1 | ALA3870315 | assay format | Scientific Literature | |
4. | ALA3870598 | ADME | Tmax in Sprague-Dawley rat at 50 mg/Kg, po | Rattus norvegicus | 1 | ALA3870315 | assay format | Scientific Literature | |
5. | ALA3870599 | ADME | Terminal half life in Sprague-Dawley rat at 50 mg/Kg, po | Rattus norvegicus | 1 | ALA3870315 | assay format | Scientific Literature | |
6. | ALA3870600 | ADME | AUC in Sprague-Dawley rat at 50 mg/Kg, po | Rattus norvegicus | 1 | ALA3870315 | assay format | Scientific Literature | |
7. | ALA3870601 | Functional | In vivo inhibition of CETP in high-fat fed syrian hamster model assessed as increase in plasma HDL-cholesterol level at 30 mg/kg, po administered once daily for 5 days measured 2 hrs post last dose relative to control | Mesocricetus auratus | 2 | ALA3870315 | organism-based format | Scientific Literature | |
8. | ALA3870602 | Functional | In vivo inhibition of CETP in high-fat fed syrian hamster model assessed as increase in plasma HDL-cholesterol level at 50 mg/kg, po administered once daily for 5 days measured 2 hrs post last dose relative to control | Mesocricetus auratus | 1 | ALA3870315 | organism-based format | Scientific Literature |