# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3865199 | Physicochemical | Solubility of the compound at pH 7 | 13 | ALA3864167 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA3865200 | ADME | Solubility of the compound in fast state simulated intestinal fluid | 3 | ALA3864167 | assay format | Scientific Literature | ||
3. | ALA3865201 | ADME | Solubility of the compound in fed state simulated intestinal fluid | 3 | ALA3864167 | assay format | Scientific Literature | ||
4. | ALA3865202 | Physicochemical | Lipophilicity, logD of compund at pH 7.4 | 7 | ALA3864167 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA3865203 | Binding | Channel blocking activity at recombinant human CaV 3.1 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins followed by CaCl2 addition by fluo-4 dye-based FLIPR assay | Homo sapiens | 97 | ALA3864167 | cell-based format | Scientific Literature | |
6. | ALA3865204 | Binding | Channel blocking activity at recombinant human CaV 3.2 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins followed by CaCl2 addition by fluo-4 dye-based FLIPR assay | Homo sapiens | 97 | ALA3864167 | cell-based format | Scientific Literature | |
7. | ALA3865205 | Binding | Channel blocking activity at recombinant human CaV 3.3 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins followed by CaCl2 addition by fluo-4 dye-based FLIPR assay | Homo sapiens | 97 | ALA3864167 | cell-based format | Scientific Literature | |
8. | ALA3865206 | ADME | Intrinsic clearance in human liver microsomes at 1 uM up to 15 mins in presence of NADPH by LC-MS-MS analysis | Homo sapiens | 97 | ALA3864167 | tissue-based format | Scientific Literature | |
9. | ALA3865207 | ADME | Intrinsic clearance in Wistar rat liver microsomes at 1 uM up to 15 mins in presence of NADPH by LC-MS-MS analysis | Rattus norvegicus | 14 | ALA3864167 | tissue-based format | Scientific Literature | |
10. | ALA5121331 | Physicochemical | Thermodynamic aqueous solubility of the compound | 163 | ALA5120754 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA5121373 | Binding | Inhibition of Cav3.3 subunit 1alpha-l(unknown origin) stably transfected in HEK293 cells measured by FLIPR assay | Homo sapiens | 2 | ALA5120754 | cell-based format | Scientific Literature | |
12. | ALA5121374 | ADME | Metabolic stability in human liver microsomes assessed as intrinsic clearance at 1 uM and measured by LC/MS-MS analysis | Homo sapiens | 2 | ALA5120754 | microsome format | Scientific Literature |