| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA879733 | F | Concentration that reduces difference in reversal of [3H]VBL accumulation between MDA-435/LCC6 and MDA-435/LCC6-MDRI cells by 50% | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 2. | ALA695434 | F | Concentration that reduces the difference in reversal of DOX accumulation between MDA-435/LCC6 and MDA-435/LCC6-MDRI cells by 50%. | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA695437 | F | To estimate the extent of resistance conferred by Pgp, the ratio of IC50 in MDA-435/LCC6-MDR1 and MDA-435/LCC6 cells (relative resistance of Pgp-positive cells) was used; no data | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA695439 | F | Ratio of effect of compound on DOX accumulation (antiPgp activity) to its intrinsic cellular toxicity; | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 5. | ALA695440 | F | Ratio of effect of compound on VBL accumulation (antiPgp activity) to its intrinsic cellular toxicity | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA694636 | F | Potency relative to progesterone in reducing the difference in reversal of DOX accumulation between MDA-435/LCC6 and MDA-435/LCC6-MDRI cells | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 7. | ALA694637 | F | Potency relative to progesterone in reducing the difference in reversing of [3H]VBL accumulation between MDA-435/LCC6 and MDA-435/LCC6-MDRI cells | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 8. | ALA711680 | F | Effect on reversal of DOX accumulation in MDA-435/LCC6 (Pgp-negative) cells. | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 9. | ALA712311 | F | Effect on reversal of [3H]- VBL accumulation in MDA-435/LCC6 (Pgp-negative) cells. | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 10. | ALA712312 | F | Growth inhibitory activity on MDA-435/LCC6 (Pgp-positive) human breast cancer cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA712314 | F | Ability of compound to inhibit MDA-435/LCC6 cell growth relative to progesterone. | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA714720 | F | Potency relative to progesterone in reversing of DOX accumulation in MDA-435/LCC6 (Pgp-negative)cells; Not determined | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA714875 | F | Potency relative to progesterone in reversing of [3H]- VBL accumulation in MDA-435/LCC6 (Pgp-negative) cells. | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 14. | ALA714876 | F | Ability of compound to inhibit MDA-435/LCC6-MDR cell growth relative to progesterone; Not determined | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 15. | ALA714878 | F | Growth inhibitory activity on MDA-435/LCC6-MDRI (Pgp-negative) human breast cancer cells | Homo sapiens | 2 | cell-based format | Scientific Literature |
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