# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA924060 | Functional | Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test | Homo sapiens | 41 | ALA1140673 | assay format | Scientific Literature | |
2. | ALA1220444 | Binding | Inhibition of beta lactamase CTX-M assessed as hydrolysis of beta lactam up to 5 mM by spectrometry analysis | 96 | ALA1212713 | assay format | Scientific Literature | ||
3. | ALA784063 | Functional | G protein activation was measured by stimulation of [35S]GTP gamma-S binding to rat adipocyte membranes | Rattus norvegicus | 9 | ALA1145993 | organism-based format | Scientific Literature | |
4. | ALA777085 | Functional | Potency required for stimulation of [35S]GTP gamma-S binding to rat spleen was determined | Rattus norvegicus | 8 | ALA1145993 | organism-based format | Scientific Literature | |
5. | ALA794202 | Functional | Relative intrinsic activity in stimulation of [35S]GTP gamma-S binding to rat adipocyte was determined | Rattus norvegicus | 9 | ALA1145993 | organism-based format | Scientific Literature | |
6. | ALA794203 | Functional | Relative intrinsic activity in stimulation of [35S]GTP gamma-S binding to rat spleen was determined | Rattus norvegicus | 8 | ALA1145993 | organism-based format | Scientific Literature | |
7. | ALA751847 | Binding | Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane. | Rattus norvegicus | 20 | ALA1145993 | cell membrane format | Scientific Literature | |
8. | ALA1002173 | Functional | Agonist activity against human GPR109a assessed as forskolin-induced cAMP accumulation | Homo sapiens | 3 | ALA1156568 | assay format | Scientific Literature | |
9. | ALA1002174 | Functional | Agonist activity against human GPR109a assessed as forskolin-induced cAMP accumulation relative to nicotinic acid | Homo sapiens | 3 | ALA1156568 | assay format | Scientific Literature | |
10. | ALA1002175 | Functional | Agonist activity against mouse GPR109a assessed as forskolin-induced cAMP accumulation | Mus musculus | 3 | ALA1156568 | assay format | Scientific Literature | |
11. | ALA1002176 | Functional | Agonist activity against mouse GPR109a assessed as forskolin-induced cAMP accumulation relative to nicotinic acid | Mus musculus | 3 | ALA1156568 | assay format | Scientific Literature | |
12. | ALA1002178 | Functional | Agonist activity against human GPR109a assessed as GTPgammaS binding | Homo sapiens | 2 | ALA1156568 | single protein format | Scientific Literature | |
13. | ALA1002179 | Functional | Agonist activity against human GPR109a assessed as GTPgammaS binding relative to nicotinic acid | Homo sapiens | 2 | ALA1156568 | single protein format | Scientific Literature | |
14. | ALA1002200 | Functional | Vasodilation effect in C57BL/6 mouse assessed as increase in blood flow relative to baseline | Mus musculus | 1 | ALA1156568 | organism-based format | Scientific Literature | |
15. | ALA988089 | Binding | Binding affinity at GPR109a | 3 | ALA1151704 | single protein format | Scientific Literature | ||
16. | ALA988092 | Functional | Intrinsic activity at GPR109a in rat spleen by [35S]GTPgammaS binding | Rattus norvegicus | 3 | ALA1151704 | tissue-based format | Scientific Literature |