| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3855036 | A | Transcellular permeability of the compound by PAMPA | 15 | ALA3853321 | assay format | Scientific Literature | ||
| 2. | ALA3855037 | B | Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresis | Homo sapiens | 15 | ALA3853321 | single protein format | Scientific Literature | |
| 3. | ALA3855038 | B | Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence assay | Rattus norvegicus | 17 | ALA3853321 | cell-based format | Scientific Literature | |
| 4. | ALA3855039 | B | Inhibition of human ERG | Homo sapiens | 2 | ALA3853321 | single protein format | Scientific Literature | |
| 5. | ALA3855040 | B | Inhibition of M1 receptor (unknown origin) | Homo sapiens | 1 | ALA3853321 | single protein format | Scientific Literature | |
| 6. | ALA3855041 | B | Inhibition of H3 receptor (unknown origin) | Homo sapiens | 1 | ALA3853321 | single protein format | Scientific Literature | |
| 7. | ALA3855042 | P | Solubility of the compound using 10%PEG200/95%D5W by high-throughput assay | 7 | ALA3853321 | small-molecule physicochemical format | Scientific Literature | ||
| 8. | ALA3855044 | F | In vivo receptor occupancy at PDGFR-beta kinase domain in rat lung at 0.1 mg/kg, it measured after 7 hrs by immunoprecipitation assay | Rattus norvegicus | 4 | ALA3853321 | organism-based format | Scientific Literature | |
| 9. | ALA3855047 | A | Drug uptake in rat lung at 0.1 mg/kg, it at 7 hrs | Rattus norvegicus | 4 | ALA3853321 | organism-based format | Scientific Literature | |
| 10. | ALA3855050 | F | In vivo receptor occupancy at PDGFR-beta kinase domain in rat lung at 0.1 mg/kg, it measured after 24 hrs by immunoprecipitation assay | Rattus norvegicus | 3 | ALA3853321 | organism-based format | Scientific Literature | |
| 11. | ALA3855052 | A | Drug uptake in rat lung at 0.1 mg/kg, it at 24 hrs | Rattus norvegicus | 3 | ALA3853321 | organism-based format | Scientific Literature | |
| 12. | ALA3855053 | A | Drug uptake in blood of rat monocrotaline model of pulmonary arterial hypertension at 0.01 mg/kg, it | Rattus norvegicus | 1 | ALA3853321 | organism-based format | Scientific Literature | |
| 13. | ALA3855054 | A | Drug uptake in blood of rat monocrotaline model of pulmonary arterial hypertension at 0.03 mg/kg, it | Rattus norvegicus | 1 | ALA3853321 | organism-based format | Scientific Literature | |
| 14. | ALA3855055 | A | Drug uptake in blood of rat monocrotaline model of pulmonary arterial hypertension at 0.1 mg/kg, it | Rattus norvegicus | 1 | ALA3853321 | organism-based format | Scientific Literature | |
| 15. | ALA3855057 | A | Half life in rat | Rattus norvegicus | 1 | ALA3853321 | assay format | Scientific Literature | |
| 16. | ALA3855058 | A | Oral bioavailability in it dosed rat | Rattus norvegicus | 1 | ALA3853321 | organism-based format | Scientific Literature | |
| 17. | ALA3855059 | F | Anti-remodeling activity in rat monocrotaline model of pulmonary arterial hypertension assessed as reduction in MCT-induced muscularization of small blood vessels in lung at 0.03 mg/kg, it administered twice daily for 7 days by histological analysis relative to control | Rattus norvegicus | 1 | ALA3853321 | organism-based format | Scientific Literature | |
| 18. | ALA3855060 | F | Anti-remodeling activity in it dosed rat monocrotaline model of pulmonary arterial hypertension assessed as reduction in MCT-induced muscularization of small blood vessels in lung administered twice daily for 7 days by histological analysis | Rattus norvegicus | 1 | ALA3853321 | organism-based format | Scientific Literature |
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