# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3870139 | A | Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid measured after 6 hrs | Chlorocebus aethiops | 10 | cell-based format | Scientific Literature | ||
2. | ALA3870140 | B | Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid measured after 6 hrs | Chlorocebus aethiops | 10 | cell-based format | Scientific Literature | ||
3. | ALA3870141 | U | Selectivity index, ratio of IC50 for African green monkey SOAT1 expressed in CHO cells to IC50 for African green monkey SOAT2 expressed in CHO cells | Chlorocebus aethiops | 8 | cell-based format | Scientific Literature | ||
4. | ALA3870142 | T | Cytotoxicity against CHO cells expressing African green monkey SOAT1 assessed as change in cell shape at 10 ug/ml | Cricetulus griseus | 15 | cell-based format | Scientific Literature | ||
5. | ALA3870143 | T | Cytotoxicity against CHO cells expressing African green monkey SOAT2 assessed as change in cell shape at 10 ug/ml | Cricetulus griseus | 15 | cell-based format | Scientific Literature | ||
6. | ALA3870144 | A | Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid at 10 ug/ml measured after 6 hrs relative to control | Chlorocebus aethiops | 13 | cell-based format | Scientific Literature | ||
7. | ALA3870145 | B | Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid at 10 ug/ml measured after 6 hrs relative to control | Chlorocebus aethiops | 13 | cell-based format | Scientific Literature |