| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3868063 | Binding | Inhibition of GST-tagged recombinant human JAK2 expressed in baculovirus using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition after 30 mins by HTRF assay | Homo sapiens | 18 | ALA3867460 | assay format | Scientific Literature | |
| 2. | ALA3868064 | Binding | Inhibition of GST-tagged recombinant human cytoplasmic JAK3 expressed in baculovirus using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition after 30 mins by HTRF assay | Homo sapiens | 18 | ALA3867460 | assay format | Scientific Literature | |
| 3. | ALA3868065 | Binding | Selectivity ratio of IC50 for human JAK3 expressed in baculovirus to IC50 for human JAK2 expressed in baculovirus | Homo sapiens | 17 | ALA3867460 | assay format | Scientific Literature | |
| 4. | ALA3868066 | Binding | Inhibition of JAK2 in human TF1 cells assessed as suppression of cell growth | Homo sapiens | 6 | ALA3867460 | cell-based format | Scientific Literature | |
| 5. | ALA3868067 | Binding | Inhibition of JAK2 V617F mutant in human HEL cells after 1 hr | Homo sapiens | 6 | ALA3867460 | cell-based format | Scientific Literature | |
| 6. | ALA3868068 | Binding | Inhibition of JAK3 in mouse HT2 cells assessed as suppression of cell growth | Mus musculus | 6 | ALA3867460 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!