| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3872645 | Functional | Antiproliferative activity against human K562/ADR cells measured after 72 hrs by CCK8 assay | Homo sapiens | 13 | ALA3872207 | cell-based format | Scientific Literature | |
| 2. | ALA3872646 | Functional | Antiproliferative activity against human K562 cells measured after 72 hrs by CCK8 assay | Homo sapiens | 13 | ALA3872207 | cell-based format | Scientific Literature | |
| 3. | ALA3872647 | Functional | Resistance index, ratio of IC50 for human K562/ADR cells to IC50 for human K562 cells | Homo sapiens | 13 | ALA3872207 | cell-based format | Scientific Literature | |
| 4. | ALA3872648 | Functional | Induction of ROS generation in human K562/ADR cells at 0.1 uM measured after 24 hrs by DCFH-DA probe based inverted fluorescence microscopy | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 5. | ALA3872649 | Functional | Induction of ROS generation in human K562/ADR cells at 0.1 uM treated 2 hrs post ROS scavenger NAC addition measured after 24 hrs by DCFH-DA probe based inverted fluorescence microscopy | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 6. | ALA3872650 | Functional | Induction of intracellular ROS accumulation in human K562/ADR cells assessed as fluorescence intensity at 0.1 uM measured after 24 hrs by DCFH-DA probe based flow cytometry relative to vehicle-treated control | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 7. | ALA3872651 | Functional | Induction of intracellular ROS accumulation in human K562/ADR cells assessed as fluorescence intensity at 0.1 uM treated 2 hrs post ROS scavenger NAC addition measured after 24 hrs by DCFH-DA probe based flow cytometry relative to vehicle-treated control | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 8. | ALA3872652 | Binding | Induction of ERK1/2 phosphorylation in human K562/ADR cells assessed as ratio of phosphorylated ERK1/2 to beta-actin level at 0.1 uM measured after 48 hrs by Western blotting (Rvb = 0.22 No_unit) | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 9. | ALA3872653 | Binding | Induction of JNK phosphorylation in human K562/ADR cells assessed as ratio of phosphorylated JNK to beta-actin level at 0.1 uM measured after 48 hrs by Western blotting (Rvb = 0.46 No_unit) | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 10. | ALA3872654 | Binding | Induction of P38 phosphorylation in human K562/ADR cells assessed as ratio of phosphorylated p38 to beta-actin level at 0.1 uM measured after 48 hrs by Western blotting method (Rvb = 0.25 No_unit) | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 11. | ALA3872655 | Binding | Induction of ERK1/2 phosphorylation in human K562/ADR cells assessed as ratio of phosphorylated ERK1/2 to beta-actin level at 0.1 uM pretreated with MAPK inhibitor U0126 for 1 hr followed by compound addition after 48 hrs by Western blotting method (Rvb = 0.22 No_unit) | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 12. | ALA3872656 | Binding | Induction of JNK phosphorylation in human K562/ADR cells assessed as ratio of phosphorylated JNK to beta-actin level at 0.1 uM pretreated with MAPK inhibitor U0126 for 1 hr followed by compound addition after 48 hrs by Western blotting method (Rvb = 0.46 No_unit) | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 13. | ALA3872657 | Binding | Induction of P38 phosphorylation in human K562/ADR cells assessed as ratio of phosphorylated p38 to beta-actin level at 0.1 uM pretreated with MAPK inhibitor U0126 for 1 hr followed by compound addition after 48 hrs by Western blotting method (Rvb = 0.25 No_unit) | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 14. | ALA3872658 | Binding | Induction of ERK1/2 phosphorylation in human K562/ADR cells assessed as ratio of phosphorylated ERK1/2 to beta-actin level at 0.1 uM pretreated with MAPK inhibitor SP600125 for 1 hr followed by compound addition after 48 hrs by Western blotting method (Rvb = 0.22 No_unit) | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 15. | ALA3872659 | Binding | Induction of JNK phosphorylation in human K562/ADR cells assessed as ratio of phosphorylated JNK to beta-actin level at 0.1 uM pretreated with MAPK inhibitor SP600125 for 1 hr followed by compound addition after 48 hrs by Western blotting method (Rvb = 0.46 No_unit) | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 16. | ALA3872660 | Binding | Induction of P38 phosphorylation in human K562/ADR cells assessed as ratio of phosphorylated p38 to beta-actin level at 0.1 uM pretreated with MAPK inhibitor SP600125 for 1 hr followed by compound addition after 48 hrs by Western blotting method (Rvb = 0.25 No_unit) | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 17. | ALA3872661 | Binding | Induction of ERK1/2 phosphorylation in human K562/ADR cells assessed as ratio of phosphorylated ERK1/2 to beta-actin level at 0.1 uM pretreated with MAPK inhibitor SB203580 for 1 hr followed by compound addition after 48 hrs by Western blotting method (Rvb = 0.22 No_unit) | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 18. | ALA3872662 | Binding | Induction of JNK phosphorylation in human K562/ADR cells assessed as ratio of phosphorylated JNK to beta-actin level at 0.1 uM pretreated with MAPK inhibitor SB203580 for 1 hr followed by compound addition after 48 hrs by Western blotting method (Rvb = 0.46 No_unit) | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 19. | ALA3872663 | Binding | Induction of P38 phosphorylation in human K562/ADR cells assessed as ratio of phosphorylated p38 to beta-actin level at 0.1 uM pretreated with MAPK inhibitor SB203580 for 1 hr followed by compound addition after 48 hrs by Western blotting method (Rvb = 0.25 No_unit) | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature | |
| 20. | ALA3872664 | Binding | Induction of ERK1/2 phosphorylation in human K562/ADR cells assessed as ratio of phosphorylated ERK1/2 to beta-actin level at 0.1 uM pretreated with ROS scavenger NAC for 2 hrs followed by compound addition after 48 hrs by Western blotting method (Rvb = 0.22 No_unit) | Homo sapiens | 1 | ALA3872207 | cell-based format | Scientific Literature |
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