# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3868512 | B | Agonist activity at human LXR-beta expressed in African green monkey CV1 cells measured after 18 to 20 hrs by luciferase reporter gene assay relative to pan agonist 1-(2,4-difluorobenzyl)-2-oxo-6-(4-phenoxyphenyl)-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
2. | ALA3868513 | B | Agonist activity at human LXR-beta expressed in African green monkey CV1 cells measured after 18 to 20 hrs by luciferase reporter gene assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
3. | ALA3868514 | B | Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analysis | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
4. | ALA3868515 | B | Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analysis | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
5. | ALA3868516 | A | Agonist activity at human LXR-alpha expressed in African green monkey CV1 cells measured after 18 to 20 hrs by luciferase reporter gene assay relative to pan agonist 1-(2,4-difluorobenzyl)-2-oxo-6-(4-phenoxyphenyl)-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
6. | ALA3868517 | B | Agonist activity at LXR-beta in human HeLa cells assessed as induction of ABCA1 by beta-galactosidase/luciferase reporter gene assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
7. | ALA3868518 | A | Agonist activity at human LXR-alpha expressed in African green monkey CV1 cells measured after 18 to 20 hrs by luciferase reporter gene assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
8. | ALA3868519 | B | Agonist activity at LXR-beta in human HeLa cells assessed as induction of ABCA1 by beta-galactosidase/luciferase reporter gene assay relative to control | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
9. | ALA3868520 | B | Agonist activity at LXR-beta in human whole blood assessed as ABCA1 gene induction by measuring ABCA1 mRNA level after 4 hrs by SYBR-Green dye-based Q-PCR analysis | Homo sapiens | 15 | tissue-based format | Scientific Literature | ||
10. | ALA3868521 | B | Agonist activity at LXR-beta in human whole blood assessed as ABCA1 gene induction by measuring ABCA1 mRNA level after 4 hrs by SYBR-Green dye-based Q-PCR analysis relative to pan agonist 2-(4-(5-(5-cyano-1-(2,4-difluorobenzyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridin-2-yl)thiophen-2-yl)-3-methylphenyl)acetic acid | Homo sapiens | 15 | tissue-based format | Scientific Literature |