#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3858842	B	Selectivity ratio of EC50 for mGlu3 (unknown origin) receptor to EC50 for human mGlu2 receptor expressed in CHO cells	Homo sapiens	1	ALA3856249	cell-based format	Scientific Literature
2.	ALA3858844	B	Positive allosteric modulation of human mGlu2 receptor expressed in CHO cell membranes assessed as potentiation of glutamate-induced effect incubated for 30 mins prior to [35S]GTPgamma addition measured after 30 mins by scintillation counting method	Homo sapiens	21	ALA3856249	cell-based format	Scientific Literature
3.	ALA3858845	B	Positive allosteric modulation of human mGlu2 receptor expressed in CHO cell membranes assessed as potentiation of glutamate-induced effect incubated for 30 mins prior to [35S]GTPgamma addition measured after 30 mins by scintillation counting method relative to control	Homo sapiens	21	ALA3856249	cell-based format	Scientific Literature
4.	ALA3858846	P	Kinetic solubility of the compound in 20% HP-beta-cyclodextrin at pH 4 by UPLC/UV method		20	ALA3856249	small-molecule physicochemical format	Scientific Literature
5.	ALA3858847	P	Kinetic solubility of the compound at pH 7 by UPLC/UV method		20	ALA3856249	small-molecule physicochemical format	Scientific Literature
6.	ALA3858848	A	Metabolic stability in human liver microsomes assessed as compound metabolized at 5 uM measured after 15 mins	Homo sapiens	20	ALA3856249	tissue-based format	Scientific Literature
7.	ALA3858849	A	Metabolic stability in rat liver microsomes assessed as compound metabolized at 5 uM measured after 15 mins	Rattus norvegicus	20	ALA3856249	tissue-based format	Scientific Literature
8.	ALA3858850	B	Inhibition of human ERG expressed in HEK293 cells assessed as reduction in maximal tail current at 3 uM and holding potential of -60 mV measured after 5 mins by patch-clamp assay	Homo sapiens	20	ALA3856249	cell-based format	Scientific Literature
9.	ALA3858851	B	Positive allosteric modulation of wild-type human mGlu2 receptor expressed in CHO-K1 cells assessed as potentiation of glutamate-induced effect incubated for 30 mins prior to [35S]GTPgamma addition measured after 30 mins by scintillation counting method	Homo sapiens	3	ALA3856249	cell-based format	Scientific Literature
10.	ALA3858852	B	Positive allosteric modulation at human mGlu2 receptor L639A mutant expressed in CHO-K1 cells assessed as potentiation of glutamate-induced effect incubated for 30 mins prior to [35S]GTPgamma addition measured after 30 mins by scintillation counting method	Homo sapiens	3	ALA3856249	cell-based format	Scientific Literature
11.	ALA3858853	B	Positive allosteric modulation at human mGlu2 receptor F643A mutant expressed in CHO-K1 cells assessed as potentiation of glutamate-induced effect incubated for 30 mins prior to [35S]GTPgamma addition measured after 30 mins by scintillation counting method	Homo sapiens	3	ALA3856249	cell-based format	Scientific Literature
12.	ALA3858854	B	Positive allosteric modulation at wild type human mGlu2 receptor L732A mutant expressed in CHO-K1 cells assessed as potentiation of glutamate-induced effect preincubated for 30 mins prior to glutamate challenge measured after 30 mins by [35S]GTP-gammaS binding assay	Homo sapiens	3	ALA3856249	cell-based format	Scientific Literature
13.	ALA3858855	B	Positive allosteric modulation at human mGlu2 receptor N735D mutant expressed in CHO-K1 cells assessed as potentiation of glutamate-induced effect incubated for 30 mins prior to [35S]GTPgamma addition measured after 30 mins by scintillation counting method	Homo sapiens	3	ALA3856249	cell-based format	Scientific Literature
14.	ALA3858856	B	Positive allosteric modulation at human mGlu2 receptor W773A mutant expressed in CHO-K1 cells assessed as potentiation of glutamate-induced effect incubated for 30 mins prior to [35S]GTPgamma addition measured after 30 mins by scintillation counting method	Homo sapiens	3	ALA3856249	cell-based format	Scientific Literature
15.	ALA3858857	B	Positive allosteric modulation at human mGlu2 receptor F776A mutant expressed in CHO-K1 cells assessed as potentiation of glutamate-induced effect incubated for 30 mins prior to [35S]GTPgamma addition measured after 30 mins by scintillation counting method	Homo sapiens	3	ALA3856249	cell-based format	Scientific Literature
16.	ALA3858858	P	Lipophilicity, log P of the compound		3	ALA3856249	small-molecule physicochemical format	Scientific Literature
17.	ALA3858859	P	Dissociation constant, pKa of the compound		3	ALA3856249	small-molecule physicochemical format	Scientific Literature
18.	ALA3858860	P	Solubility of the compound in water at pH 7.4		3	ALA3856249	small-molecule physicochemical format	Scientific Literature
19.	ALA3858861	P	Solubility of the compound in water at pH 2		3	ALA3856249	small-molecule physicochemical format	Scientific Literature
20.	ALA3858862	A	Apparent permeability across apical to basolateral side over basolateral to apical side in pig LLC-PK1 cells at 1 uM measured after 120 mins	Sus scrofa	2	ALA3856249	cell-based format	Scientific Literature