#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3858501	Binding	Inhibition of human COX-1 at 30 uM	Homo sapiens	1	ALA3856235	single protein format	Scientific Literature
2.	ALA3858502	Binding	Inhibition of human COX-2 at 30 uM	Homo sapiens	1	ALA3856235	single protein format	Scientific Literature
3.	ALA3858503	Binding	Inhibition of human mPGES-1 expressed in 293E cells assessed as reduction in conversion of PGH2 to PGE2 after 1.5 min by LC/MS analysis	Homo sapiens	10	ALA3856235	cell-based format	Scientific Literature
4.	ALA3858504	Binding	Inhibition of mPGES-1 in human A549 cells assessed as reduction in recombinant human interleukin-1 beta-induced PGE2 production preincubated for 30 mins measured after 18 hrs by ELISA	Homo sapiens	10	ALA3856235	cell-based format	Scientific Literature
5.	ALA3858505	Binding	Inhibition of mPGES-1 in human whole blood assessed as reduction in LPS-induced PGE2 production preincubated for 30 mins followed by LPS stimulation for 20 to 24 hrs by LC/MS/MS analysis	Homo sapiens	9	ALA3856235	tissue-based format	Scientific Literature
6.	ALA3858507	ADME	Inhibition of COX-2 in human A549 cells assessed as reduction in recombinant human interleukin-1 beta-induced PGI2 production up to 10 uM preincubated for 30 mins measured after 18 hrs by ELISA	Homo sapiens	10	ALA3856235	cell-based format	Scientific Literature
7.	ALA3858508	Binding	Inhibition of mPGES-1 in human whole blood assessed as reduction in LPS-induced PGF2alpha production up to 30 uM preincubated for 30 mins followed by LPS stimulation for 20 to 24 hrs by LC/MS/MS analysis	Homo sapiens	10	ALA3856235	tissue-based format	Scientific Literature
8.	ALA3858509	Binding	Inhibition of mPGES-1 in human whole blood assessed as reduction in LPS-induced TxB2 production up to 30 uM preincubated for 30 mins followed by LPS stimulation for 20 to 24 hrs by LC/MS/MS analysis	Homo sapiens	10	ALA3856235	tissue-based format	Scientific Literature
9.	ALA3858510	Binding	Inhibition of human mPGES-2	Homo sapiens	3	ALA3856235	single protein format	Scientific Literature
10.	ALA3858511	ADME	Drug metabolism in rat liver microsomes at 4 uM	Rattus norvegicus	3	ALA3856235	tissue-based format	Scientific Literature
11.	ALA3858512	ADME	Drug metabolism in dog liver microsomes at 4 uM	Canis lupus familiaris	3	ALA3856235	tissue-based format	Scientific Literature
12.	ALA3858513	ADME	Drug metabolism in human liver microsomes at 4 uM	Homo sapiens	3	ALA3856235	tissue-based format	Scientific Literature
13.	ALA3858514	ADME	Inhibition of CYP2C9 in human hepatic microsomes assessed as reduction in probe substrate metabolism at 10 uM	Homo sapiens	3	ALA3856235	assay format	Scientific Literature
14.	ALA3858515	ADME	Inhibition of CYP2D6 in human hepatic microsomes assessed as reduction in probe substrate metabolism at 10 uM	Homo sapiens	3	ALA3856235	assay format	Scientific Literature
15.	ALA3858516	ADME	Inhibition of CYP3A4 in human hepatic microsomes assessed as reduction in probe substrate metabolism at 10 uM	Homo sapiens	3	ALA3856235	assay format	Scientific Literature
16.	ALA3858517	ADME	Clearance in Beagle dog at 1 mg/kg, iv	Canis lupus familiaris	1	ALA3856235	organism-based format	Scientific Literature
17.	ALA3858518	ADME	Volume of distribution at steady state in Beagle dog at 1 mg/kg, iv	Canis lupus familiaris	1	ALA3856235	organism-based format	Scientific Literature
18.	ALA3858519	ADME	Oral bioavailability in Beagle dog at 15 mg/kg	Canis lupus familiaris	1	ALA3856235	organism-based format	Scientific Literature
19.	ALA3858520	ADME	Time at which plasma concentration remains above dog whole blood IC50 level in Beagle dog at 3 mg/kg, po	Canis lupus familiaris	1	ALA3856235	organism-based format	Scientific Literature
20.	ALA3858521	Binding	Inhibition of rat mPGES-1	Rattus norvegicus	1	ALA3856235	assay format	Scientific Literature