| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3859122 | B | Inhibition of NF-kappaB/AP-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced nitric oxide production incubated for 1 hr followed by stimulation with LPS for 24 hrs by Griess assay | Mus musculus | 5 | ALA3856253 | cell-based format | Scientific Literature | |
| 2. | ALA3859123 | B | Inhibition of NF-kappaB/AP-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production incubated for 1 hr followed by stimulation with LPS for 24 hrs by enzyme immuno assay | Mus musculus | 5 | ALA3856253 | cell-based format | Scientific Literature | |
| 3. | ALA3859124 | T | Cytotoxicity against LPS-induced mouse RAW264.7 cells assessed as decrease in cell viability after 24 hrs by MTT assay | Mus musculus | 5 | ALA3856253 | organism-based format | Scientific Literature | |
| 4. | ALA3859125 | T | Cytotoxicity against LPS-induced mouse RAW264.7 cells assessed as decrease in cell viability up to 50 uM after 24 hrs by MTT assay | Mus musculus | 1 | ALA3856253 | organism-based format | Scientific Literature | |
| 5. | ALA3859126 | B | Inhibition of NF-kappaB/AP-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced iNOS protein expression incubated for 1 hr followed by stimulation with LPS for 24 hrs by Western blot analysis | Mus musculus | 1 | ALA3856253 | cell-based format | Scientific Literature | |
| 6. | ALA3859127 | B | Inhibition of NF-kappaB/AP-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced iNOS mRNA level incubated for 4 hrs by SYBR green dye based qRT-PCR analysis | Mus musculus | 1 | ALA3856253 | cell-based format | Scientific Literature | |
| 7. | ALA3859128 | B | Inhibition of NF-kappaB/AP-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced COX-2 protein expression incubated for 1 hr followed by stimulation with LPS for 24 hrs by Western blot analysis | Mus musculus | 1 | ALA3856253 | cell-based format | Scientific Literature | |
| 8. | ALA3859129 | B | Inhibition of NF-kappaB/AP-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced COX-2 mRNA level incubated for 4 hrs by SYBR green dye based qRT-PCR analysis | Mus musculus | 1 | ALA3856253 | cell-based format | Scientific Literature | |
| 9. | ALA3859130 | B | Inhibition of NF-kappaB/AP-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced TNF-alpha production incubated for 1 hr followed by stimulation with LPS for 24 hrs by enzyme immuno assay | Mus musculus | 1 | ALA3856253 | cell-based format | Scientific Literature | |
| 10. | ALA3859131 | B | Inhibition of NF-kappaB/AP-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced IL-1beta production incubated for 1 hr followed by stimulation with LPS for 24 hrs by enzyme immuno assay | Mus musculus | 1 | ALA3856253 | cell-based format | Scientific Literature | |
| 11. | ALA3859132 | B | Inhibition of NF-kappaB/AP-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced IL-6 production incubated for 1 hr followed by stimulation with LPS for 24 hrs by enzyme immuno assay | Mus musculus | 1 | ALA3856253 | cell-based format | Scientific Literature | |
| 12. | ALA3859133 | B | Inhibition of NF-kappaB/AP-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced TNF-alpha mRNA level incubated for 4 hrs by SYBR green dye based qRT-PCR analysis | Mus musculus | 1 | ALA3856253 | cell-based format | Scientific Literature | |
| 13. | ALA3859134 | B | Inhibition of NF-kappaB/AP-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced IL-1beta mRNA level incubated for 4 hrs by SYBR green dye based qRT-PCR analysis | Mus musculus | 1 | ALA3856253 | cell-based format | Scientific Literature | |
| 14. | ALA3859135 | B | Inhibition of NF-kappaB/AP-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced IL-6 mRNA level incubated for 4 hrs by SYBR green dye based qRT-PCR analysis | Mus musculus | 1 | ALA3856253 | cell-based format | Scientific Literature | |
| 15. | ALA3859136 | B | Inhibition of LPS-induced NF-kappaB (unknown origin) activity expressed in mouse RAW264.7 cells incubated for 1 hr followed by stimulation with LPS for 18 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA3856253 | cell-based format | Scientific Literature | |
| 16. | ALA3859137 | B | Inhibition of LPS-induced AP-1 (unknown origin) activity expressed in mouse RAW264.7 cells incubated for 1 hr followed by stimulation with LPS for 18 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA3856253 | cell-based format | Scientific Literature | |
| 17. | ALA3859138 | B | Inhibition of LPS-induced NF-kappaB p65 subunit nuclear translocation in mouse RAW264.7 cells at 50 uM incubated for 1 hr followed by stimulation with LPS for 15 to 45 mins | Mus musculus | 1 | ALA3856253 | cell-based format | Scientific Literature | |
| 18. | ALA3859139 | B | Inhibition of LPS-induced NF-kappaB p65 subunit phosphorylation in mouse RAW264.7 cells at 50 uM incubated for 1 hr followed by stimulation with LPS for 15 to 45 mins | Mus musculus | 1 | ALA3856253 | cell-based format | Scientific Literature | |
| 19. | ALA3859140 | B | Inhibition of LPS-induced AP-1 c-Fos component phosphorylation in nucleus of mouse RAW264.7 cells at 50 uM incubated for 1 hr followed by stimulation with LPS for 15 to 45 mins by Western blot analysis | Mus musculus | 1 | ALA3856253 | cell-based format | Scientific Literature | |
| 20. | ALA3859141 | B | Inhibition of LPS-induced AP-1 c-Jun component phosphorylation in nucleus of mouse RAW264.7 cells at 50 uM incubated for 1 hr followed by stimulation with LPS for 15 to 45 mins by Western blot analysis | Mus musculus | 1 | ALA3856253 | cell-based format | Scientific Literature |
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