# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3861416 | F | Neuroprotective activity against H2O2-induced oxidative stress in human SH-SY5Y cells assessed as cell viability at 3 uM preincubated for 24 hrs followed by H2O2 addition for 1 hr measured after 17 hrs by MTT assay relative to control | Homo sapiens | 20 | ALA3860078 | cell-based format | Scientific Literature | |
2. | ALA3861417 | F | Neuroprotective activity in human SH-SY5Y cells assessed as protection against H2O2-induced oxidative stress at 0.3 uM preincubated for 24 hrs followed by H2O2 addition for 1 hr measured after 17 hrs by MTT assay relative to control | Homo sapiens | 2 | ALA3860078 | cell-based format | Scientific Literature | |
3. | ALA3861418 | T | Neurotoxicity against human SH-SY5Y cells assessed as reduction in cell viability at 3 to 10 uM after 24 hrs by MTT assay | Homo sapiens | 7 | ALA3860078 | cell-based format | Scientific Literature | |
4. | ALA3861420 | F | Antioxidant activity assessed as DPPH free radical scavenging activity at 3 uM after 30 mins incubation in dark | 7 | ALA3860078 | assay format | Scientific Literature | ||
5. | ALA3861423 | P | Metal chelating activity assessed as Fe2+-compound complex fromation at 3 uM incubated for 5 mins in presence of ferrous chloride hexahydrate followed by ferrozine addition measured after 10 mins | 7 | ALA3860078 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA3861424 | B | Induction of ERK1/2 phosphorylation in human SH-SY5Y cells at 3 uM preincubated for 24 hrs followed by H2O2 addition for 1 hr by pathscan sandwich immunoassay | Homo sapiens | 2 | ALA3860078 | cell-based format | Scientific Literature | |
7. | ALA3861425 | B | Induction of mTOR phosphorylation in human SH-SY5Y cells at 3 uM preincubated for 24 hrs followed by H2O2 addition for 1 hr by pathscan sandwich immunoassay | Homo sapiens | 3 | ALA3860078 | cell-based format | Scientific Literature | |
8. | ALA3861426 | B | Induction of BAD phosphorylation in human SH-SY5Y cells at 3 uM preincubated for 24 hrs followed by H2O2 addition for 1 hr by pathscan sandwich immunoassay | Homo sapiens | 4 | ALA3860078 | cell-based format | Scientific Literature | |
9. | ALA3861427 | B | Induction of PRAS40 phosphorylation in human SH-SY5Y cells at 3 uM preincubated for 24 hrs followed by H2O2 addition for 1 hr by pathscan sandwich immunoassay | Homo sapiens | 1 | ALA3860078 | cell-based format | Scientific Literature | |
10. | ALA3861428 | B | Induction of AMPKalpha phosphorylation in human SH-SY5Y cells at 3 uM preincubated for 24 hrs followed by H2O2 addition for 1 hr by pathscan sandwich immunoassay | Homo sapiens | 2 | ALA3860078 | cell-based format | Scientific Literature | |
11. | ALA3861429 | F | Antioxidant activity assessed as DPPH free radical scavenging activity after 30 mins incubation in dark by UV-Vis spectrophotometric analysis | 2 | ALA3860078 | assay format | Scientific Literature |