# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3881963 | B | Inhibition of HDAC in human HeLa nuclear extract using Fluor de Lys as substrate after 1 hr by fluorimetric method | Homo sapiens | 245 | ALA3881527 | protein format | Patent Bioactivity Data | |
2. | ALA3881966 | B | Inhibition of N-terminal GST-His6-thrombin cleavage site-fused human VEGFR2 (Asp805 to Val1356 residues) expressed in baculovirus expression system using biotinylated gastrin precursor at Tyr87 as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by DELFIA method | Homo sapiens | 60 | ALA3881527 | assay format | Patent Bioactivity Data | |
3. | ALA3882089 | B | Inhibition of N-terminal GST-His6-thrombin cleavage site-fused human PDGFRbeta (Arg561 to Leu1106 residues) assessed as decrease in biotinylated FLT3 phosphorylation at Tyr589 preincubated for 5 mins followed by substrate addition measured after 30 mins by DELFIA method | Homo sapiens | 18 | ALA3881527 | single protein format | Patent Bioactivity Data | |
4. | ALA3882092 | B | Inhibition of human N-terminal GST-tagged human c-Kit (Thr544 to Val976 residues) expressed in baculovirus expression system assessed as decrease in biotinylated KDR phosphorylation at Tyr996 preincubated for 5 mins followed by substrate addition measured after 30 mins by DELFIA method | Homo sapiens | 10 | ALA3881527 | assay format | Patent Bioactivity Data | |
5. | ALA3882093 | B | Inhibition of N-terminal GST-tagged recombinant human B-Raf (1 to 415 residues) expressed in baculovirus infected Sf21 insect cells using MEK1 as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by DELFIA | Homo sapiens | 1 | ALA3881527 | cell-based format | Patent Bioactivity Data | |
6. | ALA3882094 | B | Inhibition of N-terminal GST-tagged recombinant human C-Raf Y340D/Y341D double mutant expressed in baculovirus infected Sf21 insect cells using MEK1 as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by DELFIA | Homo sapiens | 2 | ALA3881527 | cell-based format | Patent Bioactivity Data |