| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA688027 | F | Inotropic response relative to APE (APE = 100) in electrically paced (Hz) guinea pig left atria | Cavia porcellus | 7 | organism-based format | Scientific Literature | ||
| 2. | ALA858105 | F | Inotropic responses, induced by the compound in electrically paced (Hz) guinea pig left atria | Cavia porcellus | 7 | organism-based format | Scientific Literature | ||
| 3. | ALA744763 | B | Affinity for human M1 cloned muscarinic receptor subtype expressed in CHO-K1 cells | 3 | cell-based format | Scientific Literature | |||
| 4. | ALA747664 | B | Affinity for human M3 cloned muscarinic receptor subtype expressed in CHO-K1 cells | 3 | cell-based format | Scientific Literature | |||
| 5. | ALA749857 | B | Affinity for human M4 cloned muscarinic receptor subtype expressed in CHO-K1 cells | 3 | cell-based format | Scientific Literature | |||
| 6. | ALA747003 | B | Affinity for human muscarinic acetylcholine receptor M5 subtype expressed in CHO-K1 cells | 3 | cell-based format | Scientific Literature | |||
| 7. | ALA748254 | B | Affinity for human muscarinic acetylcholine receptor M2 expressed in CHO-K1 cells | 2 | cell-based format | Scientific Literature | |||
| 8. | ALA3074473 | F | Negative ionotropic activity in electrically-paced Cavia porcellus (guinea pig) right atrium assessed as effect on rate measured immediately by isometric transducer analysis in presence of benzalkonium/prazosin relative to arecaidine propargyl ester | Cavia porcellus | 1 | tissue-based format | Scientific Literature | ||
| 9. | ALA3074474 | F | Negative ionotropic activity in electrically-paced Cavia porcellus (guinea pig) right atrium assessed as effect on rate measured immediately by isometric transducer analysis in presence of benzalkonium/prazosin | Cavia porcellus | 1 | tissue-based format | Scientific Literature | ||
| 10. | ALA3074475 | F | Negative ionotropic activity in electrically-paced Cavia porcellus (guinea pig) right atrium assessed as effect on rate measured immediately by isometric transducer analysis in absence of benzalkonium/prazosin relative to arecaidine propargyl ester | Cavia porcellus | 1 | tissue-based format | Scientific Literature | ||
| 11. | ALA3074476 | F | Negative ionotropic activity in electrically-paced Cavia porcellus (guinea pig) right atrium assessed as effect on rate measured immediately by isometric transducer analysis in absence of benzalkonium/prazosin | Cavia porcellus | 1 | tissue-based format | Scientific Literature | ||
| 12. | ALA3074477 | B | Allosteric modulation of Homo sapiens (human) recombinant muscarinic M2 receptor expressed in CHO cells assessed as inhibition of N-[3H]methylscopalamine dissociation at 20 uM incubated at 1 hr post N-[3H]methylscopalamine addition measured after 5 min by filter binding assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA3074478 | B | Allosteric modulation of Homo sapiens (human) recombinant muscarinic M2 receptor expressed in CHO cells assessed as inhibition of N-[3H]methylscopalamine dissociation incubated at 1 hr post N-[3H]methylscopalamine addition measured after 5 min by filter binding assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA3074479 | F | Allosteric modulation of Homo sapiens (human) recombinant muscarinic M5 receptor expressed in CHO cells assessed as inhibition of carbachol-induced [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA3074480 | F | Allosteric modulation of Homo sapiens (human) recombinant muscarinic M4 receptor expressed in CHO cells assessed as inhibition of carbachol-induced [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA3074481 | F | Allosteric modulation of Homo sapiens (human) recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of carbachol-induced [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA3072286 | F | Allosteric modulation of Homo sapiens (human) recombinant muscarinic M2 receptor expressed in CHO cells assessed as inhibition of carbachol-induced [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA3072287 | F | Allosteric modulation of Homo sapiens (human) recombinant muscarinic M1 receptor expressed in CHO cells assessed as inhibition of carbachol-induced [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA3072288 | F | Binding affinity to Homo sapiens (human) recombinant muscarinic M5 receptor expressed in CHO cells assessed as [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA3075762 | F | Binding affinity to Homo sapiens (human) recombinant muscarinic M4 receptor expressed in CHO cells assessed as [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature |
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