#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3881372	B	Antagonist activity at TLR1/2 in mouse RAW264.7 cells assessed as inhibition of Pam3CSK4-induced receptor activation by measuring NO production at 3 uM after 24 hrs	Mus musculus	10		cell-based format	Patent Bioactivity Data
2.	ALA3881373	B	Antagonist activity at TLR1/2 in mouse RAW264.7 cells assessed as inhibition of Pam3CSK4-induced receptor activation by measuring NO production after 24 hrs	Mus musculus	27		cell-based format	Patent Bioactivity Data
3.	ALA3881379	B	Antagonist activity at TLR3 in mouse RAW264.7 cells assessed as inhibition of Poly(I:C)-induced receptor activation by measuring NO production at 0.5 uM after 24 hrs	Mus musculus	1		cell-based format	Patent Bioactivity Data
4.	ALA3881380	B	Antagonist activity at TLR4 in mouse RAW264.7 cells assessed as inhibition of LPS-induced receptor activation by measuring NO production at 0.5 uM after 24 hrs	Mus musculus	1		cell-based format	Patent Bioactivity Data
5.	ALA3881381	B	Antagonist activity at TLR2/6 in mouse RAW264.7 cells assessed as inhibition of FSL-1-induced receptor activation by measuring NO production at 0.5 uM after 24 hrs	Mus musculus	1		cell-based format	Patent Bioactivity Data
6.	ALA3881382	B	Antagonist activity at TLR7 in mouse RAW264.7 cells assessed as inhibition of R848-induced receptor activation by measuring NO production at 0.5 uM after 24 hrs	Mus musculus	1		cell-based format	Patent Bioactivity Data
7.	ALA3881383	A	Cytotoxicity against mouse RAW264.7 cells assessed as decrease in cell viability at 8 uM by MTT assay	Mus musculus	1		cell-based format	Patent Bioactivity Data
8.	ALA3881384	B	Competitive inhibition of TLR1/2 (unknown origin) expressed in baculovirus infected Sf9 insect cells in presence of rhodamine-labeled Pam3CSK4 by fluorescence anisotropic analysis	Homo sapiens	2		cell-based format	Patent Bioactivity Data
9.	ALA3881385	F	Inhibition of Pam3CSK4-induced IL-1beta production in mouse RAW264.7 cells at 8 uM after 24 hrs by ELISA	Mus musculus	1		cell-based format	Patent Bioactivity Data
10.	ALA3881386	F	Inhibition of Pam3CSK4-induced TNF-alpha production in mouse RAW264.7 cells at 8 uM after 24 hrs by ELISA	Mus musculus	1		cell-based format	Patent Bioactivity Data
11.	ALA3881387	B	Antagonist activity at TLR1/2 in primary microglial cells (unknown origin) assessed as reduction in Pam3CSK4-induced IL-1beta mRNA expression level after 2 hrs	Homo sapiens	1		cell-based format	Patent Bioactivity Data
12.	ALA3881388	F	Antiinflammatory activity in hippocampus (unknown origin) assessed as inhibition of Pam3CSK4-induced IL-1beta mRNA expression level at 5 to 50 ng coadministered with Pam3CSK4 via intra-cisterna magna measured after 2 hrs by RT-PCR analysis	Not specified	1		assay format	Patent Bioactivity Data
13.	ALA3881389	F	Antiinflammatory activity in hippocampus (unknown origin) assessed as inhibition of Pam3CSK4-induced TNF-alpha mRNA expression level at 5 to 50 ng coadministered with Pam3CSK4 via intra-cisterna magna measured after 2 hrs by RT-PCR analysis	Not specified	1		assay format	Patent Bioactivity Data
14.	ALA3881390	F	Antiinflammatory activity in hippocampus (unknown origin) assessed as inhibition of Pam3CSK4-induced IL-6 mRNA expression level at 5 to 50 ng coadministered with Pam3CSK4 via intra-cisterna magna measured after 2 hrs by RT-PCR analysis	Not specified	1		assay format	Patent Bioactivity Data
15.	ALA4687760	B	Inhibition of Pam3CSK4-induced TLR1/TLR2 activation in mouse RAW 264.7 cells assessed as reduction in NO production incubated for 24 hrs by 2,3-diaminonaphthalene reagent based assay	Mus musculus	1		cell-based format	Scientific Literature
16.	ALA4687761	B	Inhibition of rhodamine-labeled Pam3CSK4 binding to TLR1 (unknown origin)/TLR2 (unknown origin) expressed in baculovirus infected sf9 cells incubated for 30 mins by fluorescence polarization assay	Homo sapiens	1		cell-based format	Scientific Literature