| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3867647 | B | Displacement of [3H]prazosin from human alpha1A-adrenoceptor expressed in CHO cell membranes measured after 30 mins | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 2. | ALA3867648 | A | Displacement of [3H]prazosin from human alpha1B-adrenoceptor expressed in CHO cell membranes measured after 30 mins | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 3. | ALA3867649 | B | Displacement of [3H]prazosin from human alpha1D-adrenoceptor expressed in CHO cell membranes measured after 30 mins | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 4. | ALA3867650 | B | Antagonist activity at alpha1A-adrenoceptor in Wistar rat prostatic vas deference assessed as inhibition of (-)-NE-induced contractions preincubated for 60 mins before (-)-NE challenge measured after 45 mins | Rattus norvegicus | 10 | single protein format | Scientific Literature | ||
| 5. | ALA3867651 | A | Antagonist activity at alpha1B-adrenoceptor in Wistar rat spleen assessed as inhibition of phenylphrine-induced contractions measured after 30 mins in presence of (+/-)-propranolol hydrochloride | Rattus norvegicus | 10 | single protein format | Scientific Literature | ||
| 6. | ALA3867652 | B | Antagonist activity at alpha1D-adrenoceptor in Wistar rat thoracic aorta assessed as inhibition of (-)-NE-induced contractions preincubated for 60 mins before (-)-NE challenge measured after 1 hr in presence of normetanephrine hydrochloride and (+/-)-propranolol hydrochloride | Rattus norvegicus | 10 | single protein format | Scientific Literature | ||
| 7. | ALA3867653 | B | Competitive antagonist activity at alpha1A-adrenoceptor in Wistar rat prostatic vas deference assessed as inhibition of (-)-NE-induced contractions preincubated for 60 mins before (-)-NE challenge measured after 45 mins by Schild plot analysis | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3867654 | F | Antiproliferative activity against human PC3 cells assessed as reduction in cell viability at 0.01 to 10 uM measured after 24 to 72 hrs by MTS assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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