# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3864977 | B | Inhibition of human recombinant N-terminal His-tagged DTT-activated caspase-1 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 15 | ALA3864159 | assay format | Scientific Literature | |
2. | ALA3864978 | B | Inhibition of human recombinant N-terminal His-tagged DTT-activated caspase-4 expressed in Escherichia coli using Ac-LEVD-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 15 | ALA3864159 | assay format | Scientific Literature | |
3. | ALA3864979 | B | Inhibition of human recombinant DTT-activated caspase-5 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 15 | ALA3864159 | assay format | Scientific Literature | |
4. | ALA3864994 | B | Inhibition of human recombinant cathepsin-K assessed as residual activity at 5 uM preincubated for 10 mins followed by Z-FR-AMC substrate addition by fluorescence assay relative to control | Homo sapiens | 1 | ALA3864159 | single protein format | Scientific Literature | |
5. | ALA3864995 | B | Inhibition of human recombinant cathepsin-B at 5 uM preincubated for 10 mins followed by Z-FR-AMC substrate addition by fluorescence assay | Homo sapiens | 4 | ALA3864159 | single protein format | Scientific Literature | |
6. | ALA3864996 | B | Inhibition of papaya papain at 5 uM preincubated for 10 mins followed by Suc-LLVY-AMC substrate addition by fluorescence assay relative to control | Carica papaya | 4 | ALA3864159 | single protein format | Scientific Literature | |
7. | ALA3864997 | B | Inhibition of full-length human calpain-1 at 5 uM preincubated for 10 mins followed by Suc-LLVY-AMC substrate addition by fluorescence assay relative to control | Homo sapiens | 3 | ALA3864159 | single protein format | Scientific Literature |