# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA688027 | F | Inotropic response relative to APE (APE = 100) in electrically paced (Hz) guinea pig left atria | Cavia porcellus | 7 | organism-based format | Scientific Literature | ||
2. | ALA858105 | F | Inotropic responses, induced by the compound in electrically paced (Hz) guinea pig left atria | Cavia porcellus | 7 | organism-based format | Scientific Literature | ||
3. | ALA744763 | B | Affinity for human M1 cloned muscarinic receptor subtype expressed in CHO-K1 cells | 3 | cell-based format | Scientific Literature | |||
4. | ALA747664 | B | Affinity for human M3 cloned muscarinic receptor subtype expressed in CHO-K1 cells | 3 | cell-based format | Scientific Literature | |||
5. | ALA749857 | B | Affinity for human M4 cloned muscarinic receptor subtype expressed in CHO-K1 cells | 3 | cell-based format | Scientific Literature | |||
6. | ALA747003 | B | Affinity for human muscarinic acetylcholine receptor M5 subtype expressed in CHO-K1 cells | 3 | cell-based format | Scientific Literature | |||
7. | ALA745198 | B | Binding affinity against muscarinic acetylcholine receptor M2 | 1 | single protein format | Scientific Literature | |||
8. | ALA3074477 | B | Allosteric modulation of Homo sapiens (human) recombinant muscarinic M2 receptor expressed in CHO cells assessed as inhibition of N-[3H]methylscopalamine dissociation at 20 uM incubated at 1 hr post N-[3H]methylscopalamine addition measured after 5 min by filter binding assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA3074478 | B | Allosteric modulation of Homo sapiens (human) recombinant muscarinic M2 receptor expressed in CHO cells assessed as inhibition of N-[3H]methylscopalamine dissociation incubated at 1 hr post N-[3H]methylscopalamine addition measured after 5 min by filter binding assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA3074479 | F | Allosteric modulation of Homo sapiens (human) recombinant muscarinic M5 receptor expressed in CHO cells assessed as inhibition of carbachol-induced [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA3074480 | F | Allosteric modulation of Homo sapiens (human) recombinant muscarinic M4 receptor expressed in CHO cells assessed as inhibition of carbachol-induced [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA3074481 | F | Allosteric modulation of Homo sapiens (human) recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of carbachol-induced [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA3072286 | F | Allosteric modulation of Homo sapiens (human) recombinant muscarinic M2 receptor expressed in CHO cells assessed as inhibition of carbachol-induced [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA3072287 | F | Allosteric modulation of Homo sapiens (human) recombinant muscarinic M1 receptor expressed in CHO cells assessed as inhibition of carbachol-induced [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA3072288 | F | Binding affinity to Homo sapiens (human) recombinant muscarinic M5 receptor expressed in CHO cells assessed as [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA3075762 | F | Binding affinity to Homo sapiens (human) recombinant muscarinic M4 receptor expressed in CHO cells assessed as [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA3075763 | F | Binding affinity to Homo sapiens (human) recombinant muscarinic M2 receptor expressed in CHO cells assessed as [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA3075764 | F | Binding affinity to Homo sapiens (human) recombinant muscarinic M3 receptor expressed in CHO cells assessed as [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA3075765 | F | Binding affinity to Homo sapiens (human) recombinant muscarinic M1 receptor expressed in CHO cells assessed as [35S]GTPgammaS binding | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA3074543 | F | Negative ionotropic activity in electrically-paced Cavia porcellus (guinea pig) right atrium measured after 60 min by isometric transducer analysis in presence of 4-DAMP mustard | Cavia porcellus | 2 | tissue-based format | Scientific Literature |