| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3868294 | B | Inhibition of PI3K-alpha (unknown origin) by KinaseGlo assay | Homo sapiens | 16 | ALA3867474 | single protein format | Scientific Literature | |
| 2. | ALA3868295 | B | Inhibition of PI3K-beta (unknown origin) by KinaseGlo assay | Homo sapiens | 16 | ALA3867474 | single protein format | Scientific Literature | |
| 3. | ALA3868296 | B | Inhibition of PI3K-gamma (unknown origin) by KinaseGlo assay | Homo sapiens | 16 | ALA3867474 | single protein format | Scientific Literature | |
| 4. | ALA3868297 | B | Inhibition of PI3K-delta (unknown origin) by KinaseGlo assay | Homo sapiens | 16 | ALA3867474 | single protein format | Scientific Literature | |
| 5. | ALA3868298 | B | Inhibition of myristoylated PI3K-alpha (unknown origin) overexpressed in Rat1 cells assessed as inhibition of Akt phosphorylation | Homo sapiens | 16 | ALA3867474 | cell-based format | Scientific Literature | |
| 6. | ALA3868299 | B | Inhibition of myristoylated PI3K-beta (unknown origin) overexpressed in Rat1 cells assessed as inhibition of Akt phosphorylation | Homo sapiens | 16 | ALA3867474 | cell-based format | Scientific Literature | |
| 7. | ALA3868300 | B | Inhibition of myristoylated PI3K-delta (unknown origin) overexpressed in Rat1 cells assessed as inhibition of Akt phosphorylation | Homo sapiens | 16 | ALA3867474 | cell-based format | Scientific Literature | |
| 8. | ALA3868301 | B | Inhibition of PI3K-delta in mouse splenocytes assessed as inhibition anti-IgM induced CD86 expression | Mus musculus | 16 | ALA3867474 | cell-based format | Scientific Literature | |
| 9. | ALA3868302 | B | Inhibition of PI3K-delta in rat whole blood assessed as inhibition of anti-IgM/IL4 induced CD86 expression | Rattus norvegicus | 16 | ALA3867474 | tissue-based format | Scientific Literature | |
| 10. | ALA3868303 | A | Effective permeability of the compound at pH 6.8 by PAMPA | 16 | ALA3867474 | assay format | Scientific Literature | ||
| 11. | ALA3868304 | P | Lipophilicity, log P of the compound by high-throughput assay | 16 | ALA3867474 | small-molecule physicochemical format | Scientific Literature | ||
| 12. | ALA3868305 | P | Solubility of the compound at pH 6.8 by high-throughput equilibrium analysis | 16 | ALA3867474 | small-molecule physicochemical format | Scientific Literature | ||
| 13. | ALA3868306 | B | Selectivity ratio of IC50 for myristoylated PI3K-delta (unknown origin) overexpressed in Rat1 cells to IC50 for PI3K-delta (unknown origin) | Homo sapiens | 16 | ALA3867474 | cell-based format | Scientific Literature | |
| 14. | ALA3868307 | B | Selectivity ratio of IC50 for PI3K-delta in rat whole blood to IC50 for myristoylated PI3K-delta (unknown origin) overexpressed in Rat1 cells | 16 | ALA3867474 | cell-based format | Scientific Literature | ||
| 15. | ALA4134208 | A | Inhibition of recombinant PI3Kalpha (unknown origin) using phosphatidyl inositol/n-Octyl-glucoside as substrate measured after 30 mins by KinaseGlo assay | Homo sapiens | 12 | ALA4130456 | single protein format | Scientific Literature | |
| 16. | ALA4134209 | A | Inhibition of recombinant PI3Kbeta (unknown origin) using phosphatidyl inositol/n-Octyl-glucoside as substrate measured after 60 mins by KinaseGlo assay | Homo sapiens | 12 | ALA4130456 | single protein format | Scientific Literature | |
| 17. | ALA4134210 | B | Inhibition of PI3Kgamma (unknown origin) using phosphatidyl inositol as substrate measured after 30 mins by Alexa Fluor647-labelled ADP tracer based TR-FRET assay | Homo sapiens | 12 | ALA4130456 | single protein format | Scientific Literature | |
| 18. | ALA4134211 | B | Inhibition of PI3Kdelta (unknown origin) using phosphatidyl inositol as substrate measured after 60 mins by Alexa Fluor647-labelled ADP tracer based TR-FRET assay | Homo sapiens | 12 | ALA4130456 | single protein format | Scientific Literature | |
| 19. | ALA4134212 | A | Inhibition of recombinant human myristoylated PI3Kalpha catalytic domain expressed in Rat1 cells assessed as reduction in Akt phosphorylation at Ser47 residue after 1 hr by alpha screen Surefire assay | Homo sapiens | 12 | ALA4130456 | cell-based format | Scientific Literature | |
| 20. | ALA4134213 | A | Inhibition of recombinant human myristoylated PI3Kbeta catalytic domain expressed in Rat1 cells assessed as reduction in Akt phosphorylation at Ser47 residue after 1 hr by alpha screen Surefire assay | Homo sapiens | 12 | ALA4130456 | cell-based format | Scientific Literature |
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