# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3882136 | B | Inhibition of rat NHE-3-mediated Na+ dependent H+ antiport expressed in opossum kidney cells in presence of NHE-1 antagonist EIPA by BCECF-AM dye based fluorescence assay | Rattus norvegicus | 73 | ALA3881530 | cell-based format | Patent Bioactivity Data | |
2. | ALA3882204 | F | Effect on fecal water content in Sprague-Dawley rat at 3 mg/kg administered via oral gavage measured after 16 hrs relative to control | Rattus norvegicus | 14 | ALA3881530 | organism-based format | Patent Bioactivity Data | |
3. | ALA3882208 | F | Reduction in fecal stool form in 1% psyllium diet fed Sprague-Dawley rat at 3 mg/kg administered via oral gavage measured after 16 hrs | Rattus norvegicus | 1 | ALA3881530 | organism-based format | Patent Bioactivity Data | |
4. | ALA3882209 | F | Increase in fecal water content in 1% psyllium diet fed Sprague-Dawley rat at 3 mg/kg administered via oral gavage measured after 16 hrs | Rattus norvegicus | 1 | ALA3881530 | organism-based format | Patent Bioactivity Data | |
5. | ALA3882210 | F | Decrease in urinary sodium level in 1% psyllium diet fed Sprague-Dawley rat at 3 mg/kg administered via oral gavage measured after 16 hrs by ion chromatographic analysis | Rattus norvegicus | 1 | ALA3881530 | organism-based format | Patent Bioactivity Data | |
6. | ALA3882211 | F | Antinociceptive activity in Wistar rat assessed as inhibition of partial restraint stress-induced visceral hyperalgesia at 10 mg/kg, po administered 1 hr prior to 45 to 60 mm Hg colorectal distension pressure by measuring number of abdominal contractions monitoring every 5 mins during rectal distension | Rattus norvegicus | 1 | ALA3881530 | organism-based format | Patent Bioactivity Data | |
7. | ALA3882212 | F | Increase in fecal sodium level in Sprague-Dawley rat at 3 mg/kg administered via oral gavage measured after 16 hrs by ion chromatographic analysis | Rattus norvegicus | 1 | ALA3881530 | organism-based format | Patent Bioactivity Data |