# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3863080 | Binding | Displacement of [3H]-Prazosin from alpha1 adrenergic receptor in rat brain cerebral cortex membranes by liquid scintillation counting analysis | Rattus norvegicus | 25 | ALA3861996 | cell membrane format | Scientific Literature | |
2. | ALA3863081 | Binding | Displacement of [3H]-Clonidine from alpha2 adrenergic receptor in rat brain cerebral cortex membranes by liquid scintillation counting analysis | Rattus norvegicus | 25 | ALA3861996 | cell membrane format | Scientific Literature | |
3. | ALA3863082 | Binding | Selectivity ratio of Ki for alpha2 adrenergic receptor in rat brain cerebral cortex membranes to Ki for alpha1 adrenergic receptor in rat brain cerebral cortex membranes | Rattus norvegicus | 25 | ALA3861996 | cell membrane format | Scientific Literature | |
4. | ALA3863083 | Binding | Intrinsic activity at alpha1A adrenergic receptor (unknown origin) assessed as inhibition of agonist induced effect preincubated for 30 mins followed by agonist addition measured after 5 hrs in presence of CCF4-AM by cell based beta lactamase reporter gene assay | Homo sapiens | 11 | ALA3861996 | cell-based format | Scientific Literature | |
5. | ALA3863085 | ADME | Intrinsic activity at human alpha1B adrenergic receptor expressed in CHOK1 cells co-expressing aequorin assessed as inhibition of agonist induced calcium mobilization preincubated for 15 mins followed by agonist addition measured for 20 secs in presence of coelenterazine H by luminescence assay | Homo sapiens | 11 | ALA3861996 | cell-based format | Scientific Literature | |
6. | ALA3863087 | ADME | Selectivity ratio of EC50 for human alpha1B adrenergic receptor expressed in CHOK1 cells co-expressing aequorin assessed as inhibition of agonist induced calcium mobilization to EC50 for alpha1A adrenergic receptor (unknown origin) assessed as inhibition of agonist induced effect | Homo sapiens | 11 | ALA3861996 | cell-based format | Scientific Literature |