# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3858692 | A | Cellular uptake in human PC3 cells at 30 uM measured after 24 hrs by LC-MS/MS analysis | Homo sapiens | 2 | ALA3856243 | cell-based format | Scientific Literature | |
2. | ALA3858694 | F | Antiproliferative activity against human PC3 cells assessed as reduction in cell count at 30 uM measured after 72 hrs by DAPI-staining based microscopic method | Homo sapiens | 2 | ALA3856243 | cell-based format | Scientific Literature | |
3. | ALA3858695 | B | Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)pLysS using ARTKQTARK(Me3)STGGKAPRKQL-K(Biotin)-NH2 measured after 30 mins by AlphaScreen assay | Homo sapiens | 47 | ALA3856243 | assay format | Scientific Literature | |
4. | ALA3858696 | B | Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)pLysS using biotin-labeled H3K9me3 measured after 30 mins by AlphaScreen assay | Homo sapiens | 47 | ALA3856243 | assay format | Scientific Literature | |
5. | ALA3858697 | B | Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pLysS using biotin-labeled H3K9me3 measured after 30 mins by AlphaScreen assay | Homo sapiens | 47 | ALA3856243 | assay format | Scientific Literature | |
6. | ALA3858698 | B | Antagonist activity at recombinant human N-terminal His-tagged CBX8 chromodomain (8 to 61 residues) expressed in Escherichia coli Rosetta BL21(DE3)pLysS using biotin-labeled H3K9me3 measured after 30 mins by AlphaScreen assay | Homo sapiens | 47 | ALA3856243 | assay format | Scientific Literature | |
7. | ALA3858699 | B | Antagonist activity at recombinant human N-terminal His-tagged CBX4 chromodomain (8 to 65 residues) expressed in Escherichia coli Rosetta BL21(DE3)pLysS using biotin-labeled H3K9me3 measured after 30 mins by AlphaScreen assay | Homo sapiens | 47 | ALA3856243 | assay format | Scientific Literature |