# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3854164 | F | Cytotoxicity against human LNCAP cells assessed as cell viability inhibition at 10 uM after 72 hrs by Alamar blue assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
2. | ALA3854165 | F | Potentiation of vinblastin-induced cytotoxicity against human CEM cells at 5 uM after 72 hrs by Alamar blue assay relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
3. | ALA3854166 | B | Inhibition of P-gp in human CCRF-CEM VCR/R cells assessed as potentiation of vinblastin-induced cytotoxicity at 5 uM after 72 hrs by Alamar blue assay relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
4. | ALA3854169 | B | Inhibition of LAT3 in human LNCAP cells assessed as inhibition of [3H]L-leucine uptake after 15 mins by liquid scintillation counting method | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA3854170 | F | Cytotoxicity against human CEM cells assessed as reduction in cell viability at 5 uM after 72 hrs by Alamar blue assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA3854171 | F | Cytotoxicity against human CCRF-CEM VCR/R cells assessed as reduction in cell viability at 5 uM after 72 hrs by Alamar blue assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
7. | ALA4811981 | A | Cytotoxicity against human KB/VCR cells assessed as inhibition of cell proliferation at 20 uM measured after 72 hrs by CCK8 assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
8. | ALA4811982 | A | Cytotoxicity against human KB/VCR cells assessed as inhibition of cell proliferation at 2 uM measured after 72 hrs by CCK8 assay relative to control | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
9. | ALA4811983 | B | Reversal of P-gp-mediated multidrug resistance in human KB/VCR cells assessed as potentiation of vincristine-induced antiproliferative activity by measuring vincristine IC50 at 20 uM measured after 72 hrs by CCK8 assay (Rvb = 0.78 uM) | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
10. | ALA4811984 | B | Reversal of P-gp-mediated multidrug resistance in human KB/VCR cells assessed as fold reduction in vincristine IC50 at 20 uM measured after 72 hrs by CCK8 assay relative to vincristine IC50 alone | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
11. | ALA4811985 | B | Reversal of P-gp-mediated multidrug resistance in human KB/VCR cells assessed as potentiation of vincristine-induced antiproliferative activity by measuring vincristine IC50 at 2 uM measured after 72 hrs by CCK8 assay (Rvb = 0.51 uM) | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
12. | ALA4811986 | B | Reversal of P-gp-mediated multidrug resistance in human KB/VCR cells assessed as fold reduction in vincristine IC50 at 2 uM measured after 72 hrs by CCK8 assay relative to vincristine IC50 alone | Homo sapiens | 21 | cell-based format | Scientific Literature |