| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA768750 | B | In vitro inhibitory activity against human whole blood Prostaglandin G/H synthase 1 | 8 | ALA1131765 | single protein format | Scientific Literature | ||
| 2. | ALA768751 | B | In vitro inhibitory activity against human whole cells Prostaglandin G/H synthase 1 | 5 | ALA1131765 | cell-based format | Scientific Literature | ||
| 3. | ALA763483 | B | Inhibitory activity against recombinant human prostaglandin G/H synthase 1 | 8 | ALA1147594 | single protein format | Scientific Literature | ||
| 4. | ALA768837 | B | Inhibitory potency against Prostaglandin G/H synthase 1 in human whole blood assay | 9 | ALA1147594 | tissue-based format | Scientific Literature | ||
| 5. | ALA763081 | B | In vitro inhibitory activity against human whole blood Prostaglandin G/H synthase 2 | Homo sapiens | 10 | ALA1131765 | single protein format | Scientific Literature | |
| 6. | ALA763082 | B | In vitro inhibitory activity against human whole cells (CHO) Prostaglandin G/H synthase 2 | 6 | ALA1131765 | cell-based format | Scientific Literature | ||
| 7. | ALA768962 | B | Inhibitory activity against recombinant human Prostaglandin G/H synthase 2 | 8 | ALA1147594 | single protein format | Scientific Literature | ||
| 8. | ALA769652 | B | Inhibitory potency against cyclooxygenase-2 in human whole blood assay | 8 | ALA1147594 | tissue-based format | Scientific Literature | ||
| 9. | ALA832839 | B | Inhibitory concentration against prostaglandin G/H synthase 1 in human whole blood | Homo sapiens | 2 | ALA1139640 | tissue-based format | Scientific Literature | |
| 10. | ALA876993 | B | Inhibitory concentration against prostaglandin G/H synthase 2 in human whole blood | Homo sapiens | 2 | ALA1139640 | tissue-based format | Scientific Literature | |
| 11. | ALA829659 | B | Selectivity for prostaglandin G/H synthase 2 in human whole blood | Homo sapiens | 1 | ALA1139640 | tissue-based format | Scientific Literature | |
| 12. | ALA1074446 | F | Analgesic activity in po dosed Sprague-Dawley rat assessed as inhibition of carrageenan-induced mechanical hyperalgesia relative to control | Rattus norvegicus | 2 | ALA1157608 | organism-based format | Scientific Literature | |
| 13. | ALA1074447 | F | Analgesic activity against complete Freund's adjuvant-induced Sprague-Dawley rat inflammatory pain assessed as inhibition of chronic paw swelling | Rattus norvegicus | 5 | ALA1157608 | organism-based format | Scientific Literature | |
| 14. | ALA4394091 | B | Inhibition of COX2 in guinea pig blood assessed as reduction of LPS-induced PGE2 accumulation at 10 to 10000 nM preincubated with LPS followed by compound addition and incubated for 6 or 24 hrs by EIA method | Cavia porcellus | 1 | ALA4393659 | tissue-based format | Scientific Literature | |
| 15. | ALA4394092 | B | Inhibition of COX2 in rabbit whole blood assessed as reduction of LPS-induced PGE2 accumulation at 10 to 10000 nM preincubated with LPS followed by compound addition and incubated for 6 or 24 hrs by EIA method | Oryctolagus cuniculus | 1 | ALA4393659 | tissue-based format | Scientific Literature | |
| 16. | ALA4394093 | F | Antiinflammatory activity in carrageenan-induced C57Bl/6 mouse model of inflammation assessed as inhibition of PGE2 accumulation in air pouch at 0.1 to 10 mg/kg , po pretreated with carrageenan for 20 hrs and followed by compound administration and measured after 4 hrs | Mus musculus | 1 | ALA4393659 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!