# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3880148 | Binding | Inhibition of A-Raf (unknown origin) assessed as decrease in biotin-tagged MEK1 phosphorylation after 45 mins | Homo sapiens | 34 | ALA3879902 | single protein format | Patent Bioactivity Data | |
2. | ALA3880149 | Binding | Inhibition of B-Raf (unknown origin) assessed as decrease in biotin-tagged MEK1 phosphorylation after 45 mins | Homo sapiens | 90 | ALA3879902 | single protein format | Patent Bioactivity Data | |
3. | ALA3880150 | Binding | Inhibition of B-Raf V600E mutant (unknown origin) assessed as decrease in biotin-tagged MEK1 phosphorylation after 45 mins | Homo sapiens | 91 | ALA3879902 | single protein format | Patent Bioactivity Data | |
4. | ALA3880151 | Binding | Inhibition of C-Raf1 (unknown origin) assessed as decrease in biotin-tagged MEK1 phosphorylation after 45 mins | Homo sapiens | 70 | ALA3879902 | single protein format | Patent Bioactivity Data | |
5. | ALA3880153 | Functional | Cytotoxicity against human A375 cells expressing B-RAF V600E mutant assessed as growth inhibition after 3 days by ATPlite 1 step luminescence assay | Homo sapiens | 90 | ALA3879902 | cell-based format | Patent Bioactivity Data | |
6. | ALA3880154 | Functional | Cytotoxicity against human COLO205 cells expressing B-RAF V600E mutant assessed as growth inhibition after 3 days by ATPlite 1 step luminescence assay | Homo sapiens | 74 | ALA3879902 | cell-based format | Patent Bioactivity Data | |
7. | ALA3880158 | Functional | Cytotoxicity against human SK-MEL-2 cells expressing Ras mutant assessed as growth inhibition at 10 uM after 3 days by ATPlite 1 step luminescence assay | Homo sapiens | 41 | ALA3879902 | cell-based format | Patent Bioactivity Data | |
8. | ALA3880159 | Functional | Cytotoxicity against human SW620 cells expressing Ras mutant assessed as growth inhibition at 10 uM after 3 days by ATPlite 1 step luminescence assay | Homo sapiens | 62 | ALA3879902 | cell-based format | Patent Bioactivity Data |