# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3860325 | B | Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins | Homo sapiens | 11 | ALA3860036 | assay format | Scientific Literature | |
2. | ALA3860326 | B | Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli at 32 uM preincubated for 10 mins followed by pNPP substrate addition measured after 30 mins relative to control | Homo sapiens | 1 | ALA3860036 | assay format | Scientific Literature | |
3. | ALA4349871 | B | Inhibition of SOAT-mediated oleic acid-induced [14C]cholesterol ester accumulation in CHOK1 cells after 6 hrs using [14C]oleic acid by Oil Red O staining-based microscopic analysis | Cricetulus griseus | 14 | ALA4346732 | cell-based format | Scientific Literature | |
4. | ALA4349872 | B | Inhibition of DGAT-mediated oleic acid-induced [14C]neutral lipid synthesis in CHOK1 cells after 6 hrs using [14C]oleic acid by Oil Red O staining-based microscopic analysis | Cricetulus griseus | 14 | ALA4346732 | cell-based format | Scientific Literature | |
5. | ALA4349873 | A | Cytotoxicity against CHOK1 cells assessed as reduction in cell viability | Cricetulus griseus | 14 | ALA4346732 | cell-based format | Scientific Literature | |
6. | ALA4349874 | B | Inhibition of SOAT in CHOK1 cell microsomal fraction using [1-14C]oleoyl-CoA as substrate measured after 5 mins by TLC based method | Cricetulus griseus | 2 | ALA4346732 | assay format | Scientific Literature | |
7. | ALA4349875 | B | Inhibition of DGAT in CHOK1 cell microsomal fraction using [14C]palmitoyl-CoA as substrate measured after 15 mins TLC based method | Cricetulus griseus | 2 | ALA4346732 | assay format | Scientific Literature | |
8. | ALA4349876 | B | Inhibition of African green monkey SOAT1 expressed in CHO cells using [1-14C]oleic acid incubated for 6 hrs by TLC based method | Chlorocebus aethiops | 2 | ALA4346732 | cell-based format | Scientific Literature | |
9. | ALA4349877 | B | Inhibition of African green monkey SOAT2 expressed in CHO cells using [1-14C]oleic acid incubated for 6 hrs by TLC based method | Chlorocebus aethiops | 2 | ALA4346732 | cell-based format | Scientific Literature | |
10. | ALA4349878 | B | Inhibition of SOAT1 in CHO cell microsomal fraction using [1-14C]oleoyl-CoA as substrate measured after 5 mins by TLC based method | Cricetulus griseus | 2 | ALA4346732 | cell-based format | Scientific Literature | |
11. | ALA4349879 | B | Inhibition of SOAT2 in CHO cell microsomal fraction using [1-14C]oleoyl-CoA as substrate measured after 5 mins by TLC based method | Cricetulus griseus | 2 | ALA4346732 | cell-based format | Scientific Literature |