| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3855894 | B | Inhibition of human PI3Kdelta (R108 to Q1044 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assay | Homo sapiens | 21 | assay format | Scientific Literature | ||
| 2. | ALA3855895 | B | Inhibition of human PI3Kgamma (S144 to A1102 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assay | Homo sapiens | 21 | assay format | Scientific Literature | ||
| 3. | ALA4185634 | B | Inhibition of recombinant full length His-tagged human Aurora A expressed in baculovirus expression system by Z'LYTE assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 4. | ALA4185635 | B | Inhibition of recombinant full length His-tagged human Aurora B expressed in baculovirus expression system by Z'LYTE assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 5. | ALA4185636 | B | Inhibition of recombinant full length GST-tagged human Aurora C expressed in baculovirus expression system by Z'LYTE assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 6. | ALA4185637 | B | Inhibition of Aurora A auto-phosphorylation in human HCT116 cells after 4 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4185638 | B | Inhibition of Aurora B in human HCT116 cells assessed as reduction in histone H3 phosphorylation at S10 residues after 4 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4185639 | F | Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4185640 | F | Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4185641 | A | Cytotoxicity against human HEK293 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4185642 | F | Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4185643 | F | Cytotoxicity against human HCT116 cells assessed as reduction in cell viability up to 33.3 uM after 72 hrs by CellTiter-Glo assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA4185644 | A | Cytotoxicity against human HEK293 cells assessed as reduction in cell viability up to 33.3 uM after 72 hrs by CellTiter-Glo assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA4185645 | F | Cytotoxicity against human PC3 cells assessed as reduction in cell viability up to 33.3 uM after 72 hrs by CellTiter-Glo assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4185646 | A | Half life in mouse hepatic microsomes at 1 mg/ml | Mus musculus | 2 | microsome format | Scientific Literature | ||
| 16. | ALA4185647 | B | Inhibition of BRD4 (unknown origin) by AlphaScreen assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 17. | ALA4185648 | B | Inhibition of GST-tagged human PLK4 (1 to 836 residues) by Lanthascreen binding assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 18. | ALA4185649 | B | Inhibition of recombinant GST-tagged human LRRK2 (970 to 2527 residues) catalytic domain expressed in baculovirus expression system by ADAPTA assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 19. | ALA4185651 | B | Binding affinity to human wild-type AAK1 (G25 to L333 residues) expressed in Escherichia coli BL21 at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 20. | ALA4185652 | B | Binding affinity to wild-type human non-phosphorylated ABL1 (S229 to K512 residues) expressed in HEK293 cells at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature |
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