| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3855086 | A | Metabolic stability in human serum at 10 mg/ml at 37 degC after 2 hrs by HPLC analysis | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 2. | ALA3855089 | P | Aqueous solubility of compound in 50 mM sodium succinate buffer at >1 mM at pH 5 by 1D 1H NMR spectroscopic analysis | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA3855090 | B | Binding affinity to CD47 receptor in human NT.115-labeled MEC1 cell membranes after 5 mins by MST assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 4. | ALA3855091 | B | Binding affinity to CD47 receptor in human biotinylated MEC1 cell membranes by biolayer interferometry | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 5. | ALA3855092 | F | Induction of programmed cell death in human MEC1 cells at 200 uM after 2 hrs by Annexin-V/propidium iodide staining based FACS analysis | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 6. | ALA3855093 | F | Induction of programmed cell death in human MEC1 cells at 50 uM after 2 hrs by Annexin-V/propidium iodide staining based FACS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3855094 | F | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 200 uM after 2 hrs by Annexin-V/propidium iodide staining based FACS analysis (Rvb = 2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3855095 | F | Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 200 uM after 2 hrs by Annexin-V/propidium iodide staining based FACS analysis (Rvb = 5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3855096 | F | Induction of apoptosis in human MCF7 cells assessed as early apoptotic cells at 200 uM after 2 hrs by Annexin-V/propidium iodide staining based FACS analysis (Rvb = 4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3855097 | F | Induction of apoptosis in human MCF7 cells assessed as late apoptotic cells at 200 uM after 2 hrs by Annexin-V/propidium iodide staining based FACS analysis (Rvb = 22%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3855098 | F | Induction of apoptosis in human HCT116 cells assessed as early apoptotic cells at 200 uM after 2 hrs by Annexin-V/propidium iodide staining based FACS analysis (Rvb = 4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3855099 | F | Induction of apoptosis in human HCT116 cells assessed as late apoptotic cells at 200 uM after 2 hrs by Annexin-V/propidium iodide staining based FACS analysis (Rvb = 5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3855100 | F | Induction of programmed cell death in human A549 cells at 50 uM after 2 hrs by Annexin-V/propidium iodide staining based FACS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3855101 | F | Induction of programmed cell death in human HCT116 cells at 50 uM after 2 hrs by Annexin-V/propidium iodide staining based FACS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3855102 | F | Induction of programmed cell death in human HCT116 cells at 200 uM after 2 hrs by Annexin-V/propidium iodide staining based FACS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3855103 | F | Induction of programmed cell death in human A549 cells after 2 hrs by Annexin-V/propidium iodide staining based FACS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3855104 | F | Induction of programmed cell death in human HCT116 cells after 2 hrs by Annexin-V/propidium iodide staining based FACS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3855105 | F | Induction of programmed cell death in human MCF7 cells after 2 hrs by Annexin-V/propidium iodide staining based FACS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4415101 | B | Binding affinity to CD47 in biotinylated human MEC1 cell membranes by biolayer interferometry | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 20. | ALA4415102 | F | Cytotoxicity against human MEC1 cells assessed as induction of cell death at 200 uM after 6 hrs by annexin V/propidium iodide staining based flow cytometric analysis relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature |
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