# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3883092 | Functional | Agonist activity at human recombinant EP3A receptor expressed in HEK293 cells assessed as effect on calcium accumulation by Fluo-4 AM dye based FLIPR assay | Homo sapiens | 114 | ALA3882734 | cell-based format | Patent Bioactivity Data | |
2. | ALA3883093 | Binding | Displacement of [3H]PGE2 from from human EP2 receptor expressed in HEK293 cells at pH 7.3 membranes incubated for 60 mins | Homo sapiens | 55 | ALA3882734 | cell-based format | Patent Bioactivity Data | |
3. | ALA3883096 | Functional | Agonist activity at human recombinant FP receptor expressed in HEK293 cells assessed as effect on calcium accumulation by Fluo-4 AM dye based FLIPR assay | Homo sapiens | 96 | ALA3882734 | cell-based format | Patent Bioactivity Data | |
4. | ALA3883097 | Functional | Agonist activity at human recombinant EP1 receptor expressed in HEK293 cells assessed as effect on calcium accumulation by Fluo-4 AM dye based FLIPR assay | Homo sapiens | 95 | ALA3882734 | cell-based format | Patent Bioactivity Data | |
5. | ALA3883098 | Functional | Agonist activity at human recombinant EP2 receptor expressed in HEK293 cells assessed as effect on calcium accumulation by Fluo-4 AM dye based FLIPR assay | Homo sapiens | 140 | ALA3882734 | cell-based format | Patent Bioactivity Data | |
6. | ALA3883100 | Functional | Agonist activity at human recombinant TP receptor expressed in HEK293 cells assessed as effect on calcium accumulation by Fluo-4 AM dye based FLIPR assay | Homo sapiens | 114 | ALA3882734 | cell-based format | Patent Bioactivity Data | |
7. | ALA3883101 | Functional | Agonist activity at human recombinant IP receptor expressed in HEK293 cells assessed as effect on calcium accumulation by Fluo-4 AM dye based FLIPR assay | Homo sapiens | 114 | ALA3882734 | cell-based format | Patent Bioactivity Data | |
8. | ALA3883102 | Functional | Agonist activity at human recombinant DP receptor expressed in HEK293 cells assessed as effect on calcium accumulation by Fluo-4 AM dye based FLIPR assay | Homo sapiens | 112 | ALA3882734 | cell-based format | Patent Bioactivity Data | |
9. | ALA3883113 | Functional | Reduction in intraocular pressure in Beagle dog assessed as maximal change in intraocular pressure at 0.3% administered topically to one eye immediately after first intraocular pressure reading by pneumatonometry | Canis lupus familiaris | 3 | ALA3882734 | tissue-based format | Patent Bioactivity Data | |
10. | ALA3883114 | Functional | Effect on ocular surface hyperemia in Beagle dog assessed as maximum ocular surface hyperemia score assigned value at 0.3% administered topically to one eye immediately after first intraocular pressure reading by pneumatonometry | Canis lupus familiaris | 3 | ALA3882734 | tissue-based format | Patent Bioactivity Data |