# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3859969 | Functional | Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated with compound followed by LPA addition by fluorescence assay | Homo sapiens | 32 | ALA3856289 | cell-based format | Scientific Literature | |
2. | ALA4144007 | Functional | Antagonist activity at recombinant human LPA1 expressed in CHO cells assessed as reduction in LPA-induced intracellular calcium level pretreated followed by LPA addition by Fura-2-AM dye based fluorescence assay | Homo sapiens | 19 | ALA4138255 | cell-based format | Scientific Literature | |
3. | ALA4144008 | ADME | Half life in rat microsomes in presence of NADPH | Rattus norvegicus | 9 | ALA4138255 | microsome format | Scientific Literature | |
4. | ALA4144009 | ADME | Half life in human microsomes in presence of NADPH | Homo sapiens | 9 | ALA4138255 | microsome format | Scientific Literature |