# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3868772 | Binding | Inhibition of PI3Kalpha (unknown origin) using diC8 PIP2 as substrate after 80 mins by ADP-glo assay | Homo sapiens | 25 | ALA3868583 | single protein format | Scientific Literature | |
2. | ALA3868773 | Binding | Inhibition of PI3Kbeta (unknown origin) using diC8 PIP2 as substrate after 60 mins by ADP-glo assay | Homo sapiens | 25 | ALA3868583 | single protein format | Scientific Literature | |
3. | ALA3868774 | Binding | Inhibition of PI3Kdelta (unknown origin) using diC8 PIP2 as substrate after 120 mins by ADP-glo assay | Homo sapiens | 25 | ALA3868583 | single protein format | Scientific Literature | |
4. | ALA3868775 | Binding | Inhibition of PI3Kgamma (unknown origin) using diC8 PIP2 as substrate after 75 mins by ADP-glo assay | Homo sapiens | 25 | ALA3868583 | single protein format | Scientific Literature | |
5. | ALA3868776 | Binding | Inhibition of human mTOR at 1 uM using 4EBP1 as substrate preincubated followed by [33P]-ATP addition measured after 2 hrs by filter binding method | Homo sapiens | 25 | ALA3868583 | single protein format | Scientific Literature | |
6. | ALA3868777 | Binding | Inhibition of PI3Kalpha (unknown origin) using diC8 PIP2 as substrate at 0.5 uM after 80 mins by ADP-glo assay | Homo sapiens | 26 | ALA3868583 | single protein format | Scientific Literature | |
7. | ALA3868778 | Binding | Selectivity ratio of IC50 for PI3Kdelta (unknown origin) to IC50 for PI3Kalpha (unknown origin) | Homo sapiens | 25 | ALA3868583 | assay format | Scientific Literature | |
8. | ALA3868779 | Binding | Selectivity ratio of IC50 for PI3Kgamma (unknown origin) to IC50 for PI3Kalpha (unknown origin) | Homo sapiens | 24 | ALA3868583 | assay format | Scientific Literature | |
9. | ALA3868780 | Binding | Selectivity ratio of IC50 for PI3Kbeta (unknown origin) to IC50 for PI3Kalpha (unknown origin) | Homo sapiens | 25 | ALA3868583 | assay format | Scientific Literature | |
10. | ALA3868781 | Binding | Inhibition of PI3Kbeta (unknown origin) using diC8 PIP2 as substrate up to 20 uM after 60 mins by ADP-glo assay | Homo sapiens | 1 | ALA3868583 | single protein format | Scientific Literature | |
11. | ALA3868782 | Functional | Cytotoxicity against human HL60 cells assessed as cell growth inhibition after 48 hrs by MTT assay | Homo sapiens | 25 | ALA3868583 | cell-based format | Scientific Literature | |
12. | ALA3868783 | Functional | Cytotoxicity against human A375 cells assessed as cell growth inhibition after 48 hrs by MTT assay | Homo sapiens | 25 | ALA3868583 | cell-based format | Scientific Literature | |
13. | ALA3868784 | Functional | Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by MTT assay | Homo sapiens | 25 | ALA3868583 | cell-based format | Scientific Literature | |
14. | ALA3868785 | Functional | Cytotoxicity against human PANC1 cells assessed as cell growth inhibition after 48 hrs by MTT assay | Homo sapiens | 25 | ALA3868583 | cell-based format | Scientific Literature | |
15. | ALA3868786 | Functional | Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay | Homo sapiens | 25 | ALA3868583 | cell-based format | Scientific Literature | |
16. | ALA3868787 | Functional | Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 6 hrs by MTT assay | Homo sapiens | 1 | ALA3868583 | cell-based format | Scientific Literature | |
17. | ALA3868788 | Functional | Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 12 hrs by MTT assay | Homo sapiens | 1 | ALA3868583 | cell-based format | Scientific Literature | |
18. | ALA3868789 | Functional | Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 24 hrs by MTT assay | Homo sapiens | 1 | ALA3868583 | cell-based format | Scientific Literature | |
19. | ALA3868790 | Toxicity | Cytotoxicity against human FR2 cells assessed as cell growth inhibition after 48 hrs by MTT assay | Homo sapiens | 2 | ALA3868583 | cell-based format | Scientific Literature | |
20. | ALA3868791 | Toxicity | Cytotoxicity against HEK293 cells assessed as cell growth inhibition after 48 hrs by MTT assay | Homo sapiens | 2 | ALA3868583 | cell-based format | Scientific Literature |