# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3880443 | Binding | Inhibition of trypsin-activated recombinant human collagenase 1 preincubated with protein followed by addition of DNP-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(NMA)-NH2 as substrate measured after 20 mins by fluorescence analysis | Homo sapiens | 26 | ALA3880381 | single protein format | Patent Bioactivity Data | |
2. | ALA3880444 | Binding | Inhibition of APMA-activated recombinant human collagenase 3 preincubated with protein followed by addition of DNP-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(NMA)-NH2 as substrate measured every 5 mins for 1 hr by fluorescence analysis | Homo sapiens | 26 | ALA3880381 | single protein format | Patent Bioactivity Data | |
3. | ALA3880445 | Binding | Inhibition of aggrecanase in primary porcine chondrocytes assessed as inhibition of 35S-proteoglycan release measured after 9 to 12 hrs by liquid scintillation counting method | Sus scrofa | 26 | ALA3880381 | cell-based format | Patent Bioactivity Data | |
4. | ALA3880446 | Binding | Inhibition of TACE in human mononuclear cells assessed as inhibition of LPS-induced TNF-alpha production measured after 4 hrs in presence of LPS by ELISA | Homo sapiens | 26 | ALA3880381 | cell-based format | Patent Bioactivity Data |