| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3862616 | B | Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentration by Fluo-4AM dye-based spectrofluorometry relative to ionomycin | Rattus norvegicus | 15 | cell-based format | Scientific Literature | ||
| 2. | ALA3862617 | B | Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentration by Fluo-4AM dye-based spectrofluorometry | Rattus norvegicus | 15 | cell-based format | Scientific Literature | ||
| 3. | ALA3862618 | B | Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincubated for 5 mins prior to thymol-stimulation by Fluo-4AM dye-based spectrofluorometry | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
| 4. | ALA3862619 | B | Inhibition of TNFalpha-induced NFkappaB activation in mouse NIH-3T3 cells expressing NFkappaB (unknown origin) preincubated for 15 mins followed by TNFalpha addition measured after 6 hrs by luciferase reporter gene assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 5. | ALA3862620 | B | Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma addition measured after 6 hrs by luciferase reporter gene assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 6. | ALA3862621 | B | Agonist activity at mouse YFP-tagged TRPV3 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-2-AM dye based microscopic analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3862622 | B | Inhibition of NFkappaB p65 activation (unknown origin) expressed in human HeLa cells assessed as inhibition of TNFalpha-induced NFkappaB p65 nuclear accumulation pretreated with cells followed by TNFalpha addition by DAPI staining based microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!