# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3881216 | F | Antagonist activity at PGD2 receptor in human platelets assessed as inhibition of PGD2-mediated cAMP accumulation preincubated for 5 mins followed by PGD2 addition measured after 2 mins by HTRF assay | Homo sapiens | 79 | assay format | Patent Bioactivity Data | ||
2. | ALA3881217 | B | Displacement of [3H]-PGD2 from PGD2 receptor in human platelet membranes after 2 hrs by micro beta scintillation counting analysis | Homo sapiens | 53 | cell membrane format | Patent Bioactivity Data | ||
3. | ALA3881218 | F | Agonist activity at human EP1 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
4. | ALA3881219 | F | Agonist activity at human EP1 receptor expressed in HEK293 cells assessed as increase in cAMP production | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
5. | ALA3881220 | F | Agonist activity at human EP2 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
6. | ALA3881221 | F | Agonist activity at human EP2 receptor expressed in HEK293 cells assessed as increase in cAMP production | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
7. | ALA3881222 | F | Agonist activity at human EP3 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
8. | ALA3881223 | F | Agonist activity at human EP3 receptor expressed in HEK293 cells assessed as increase in cAMP production | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
9. | ALA3881224 | F | Agonist activity at human EP4 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
10. | ALA3881225 | F | Agonist activity at human EP4 receptor expressed in HEK293 cells assessed as increase in cAMP production | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
11. | ALA3881226 | F | Agonist activity at human FP receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
12. | ALA3881227 | F | Agonist activity at human FP receptor expressed in HEK293 cells assessed as increase in cAMP production | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
13. | ALA3881228 | F | Agonist activity at human TP receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
14. | ALA3881229 | F | Agonist activity at human TP receptor expressed in HEK293 cells assessed as increase in cAMP production | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
15. | ALA3881230 | F | Agonist activity at human IP receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
16. | ALA3881231 | F | Agonist activity at human IP receptor expressed in HEK293 cells assessed as increase in cAMP production | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
17. | ALA3881232 | B | Selectivity ratio of IC50 for PGD2 receptor in human platelets to IC50 for human EP1 receptor expressed in HEK293 cells by cAMP accumulation assay | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
18. | ALA3881233 | B | Selectivity ratio of IC50 for PGD2 receptor in human platelets to IC50 for human EP2 receptor expressed in HEK293 cells by cAMP accumulation assay | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
19. | ALA3881234 | B | Selectivity ratio of IC50 for PGD2 receptor in human platelets to IC50 for human EP3 receptor expressed in HEK293 cells by cAMP accumulation assay | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data | ||
20. | ALA3881235 | B | Selectivity ratio of IC50 for PGD2 receptor in human platelets to IC50 for human EP4 receptor expressed in HEK293 cells by cAMP accumulation assay | Homo sapiens | 79 | cell-based format | Patent Bioactivity Data |