# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3881323 | F | Agonist activity at human recombinant prostacyclin receptor expressed in CHO-K1 cells assessed as induction of cAMP accumulation incubated for 1 hr by HTRF assay | Homo sapiens | 100 | cell-based format | Patent Bioactivity Data | ||
2. | ALA3881324 | F | Inhibition of ADP-induced platelet aggregation in human platelet rich plasma pre-incubated for 1 min before ADP addition and measured 3 mins post ADP addition by aggregometry | Homo sapiens | 100 | cell-free format | Patent Bioactivity Data | ||
3. | ALA4005261 | F | Intrinsic activity at recombinant rat IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level at 10 uM after 1 hr incubation by HTRF method relative to iloprost | Rattus norvegicus | 20 | cell-based format | Scientific Literature | ||
4. | ALA4005262 | F | Agonist activity at recombinant rat IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by HTRF method | Rattus norvegicus | 23 | cell-based format | Scientific Literature | ||
5. | ALA4005263 | F | Intrinsic activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level at 10 uM after 1 hr incubation by HTRF method relative to iloprost | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
6. | ALA4005264 | F | Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by HTRF method | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
7. | ALA4005265 | F | Agonist activity at recombinant human DP1 receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by HTRF method | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
8. | ALA4005266 | F | Intrinsic activity at recombinant human DP1 receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by HTRF method relative to prostaglandin D2 | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
9. | ALA4005267 | B | Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregation | Homo sapiens | 23 | assay format | Scientific Literature | ||
10. | ALA4005268 | A | Half life in human microsomes | Homo sapiens | 23 | assay format | Scientific Literature | ||
11. | ALA4005269 | A | Half life in rat microsomes | Rattus norvegicus | 23 | assay format | Scientific Literature | ||
12. | ALA4005345 | B | Ratio of IC50 for IP receptor in human primary platelets to EC50 for recombinant human IP receptor expressed in CHO-K1 cells | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
13. | ALA4005346 | B | Selectivity ratio of EC50 for recombinant rat IP receptor expressed in CHO-K1 cells to EC50 for recombinant human IP receptor expressed in CHO-K1 cells | 21 | cell-based format | Scientific Literature |