# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3860801 | F | Agonist activity at human KISS1R expressed in CHO/dhfr cells assessed as increase in intracellular Ca2+ levels measured for 180 secs by Fluo 3-AM dye based FLIPR assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
2. | ALA3860802 | F | Agonist activity at rat KISS1R expressed in CHO/dhfr cells assessed as increase in intracellular Ca2+ levels measured for 180 secs by Fluo 3-AM dye based FLIPR assay | Rattus norvegicus | 36 | cell-based format | Scientific Literature | ||
3. | ALA3860803 | F | Inhibition of testosterone levels in CD(SD) rat assessed as plasma testosterone level <0.04 ng/ml at 0.1 nmol/hr, sc administered continuously for 6 days through alzet osmotic pump measured after 6 days by radio-immunoassay | Rattus norvegicus | 35 | organism-based format | Scientific Literature | ||
4. | ALA3860804 | F | Inhibition of testosterone levels in CD(SD) rat assessed as plasma testosterone level <0.04 ng/ml at 0.03 nmol/hr, sc administered continuously for 6 days through alzet osmotic pump measured after 6 days by radio-immunoassay | Rattus norvegicus | 30 | organism-based format | Scientific Literature | ||
5. | ALA3860805 | F | Inhibition of testosterone levels in CD(SD) rat assessed as plasma testosterone level <0.04 ng/ml at 0.01 nmol/hr, sc administered continuously for 6 days through alzet osmotic pump measured after 6 days by radio-immunoassay | Rattus norvegicus | 28 | organism-based format | Scientific Literature | ||
6. | ALA3860806 | F | Inhibition of testosterone levels in CD(SD) rat assessed as plasma testosterone level <0.04 ng/ml at 0.003 nmol/hr, sc administered continuously for 6 days through alzet osmotic pump measured after 6 days by radio-immunoassay | Rattus norvegicus | 35 | organism-based format | Scientific Literature | ||
7. | ALA3860823 | P | Solubility of the compound in water at 20 mg/ml | 7 | small-molecule physicochemical format | Scientific Literature |