# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3871160 | Binding | Positive allosteric modulation of GluN1/GluN2A receptor (unknown origin) expressed in CHO cells assessed as increase in glutamate-induced calcium flux measured at time interval of 5 mins in presence of saturating glycine by calcium dye-based fluorescence assay | Homo sapiens | 15 | ALA3870360 | cell-based format | Scientific Literature | |
2. | ALA3871161 | Binding | Positive allosteric modulation of GluN1/GluN2A receptor (unknown origin) expressed in CHO cells assessed as increase in glutamate-induced calcium flux at 125 uM measured at time interval of 5 mins in presence of saturating glycine by calcium dye-based fluorescence assay relative to glutamate | Homo sapiens | 15 | ALA3870360 | cell-based format | Scientific Literature | |
3. | ALA3871162 | ADME | Positive allosteric modulation of human GluA2 receptor flip isoform assessed as increase in glutamate-induced calcium flux measured at time interval of 5 mins in presence of saturating glycine by calcium dye-based fluorescence assay | Homo sapiens | 11 | ALA3870360 | single protein format | Scientific Literature | |
4. | ALA3871163 | ADME | Positive allosteric modulation of human GluA2 receptor flip isoform assessed as increase in glutamate-induced calcium flux at 125 uM measured at time interval of 5 mins in presence of saturating glycine by calcium dye-based fluorescence assay relative to glutamate | Homo sapiens | 15 | ALA3870360 | single protein format | Scientific Literature | |
5. | ALA3871164 | ADME | Positive allosteric modulation of human GluA2 receptor flop isoform assessed as increase in glutamate-induced calcium flux measured at time interval of 5 mins in presence of saturating glycine by calcium dye-based fluorescence assay | Homo sapiens | 11 | ALA3870360 | single protein format | Scientific Literature | |
6. | ALA3871165 | ADME | Positive allosteric modulation of human GluA2 receptor flop isoform assessed as increase in glutamate-induced calcium flux at 125 uM measured at time interval of 5 mins in presence of saturating glycine by calcium dye-based fluorescence assay relative to glutamate | Homo sapiens | 15 | ALA3870360 | single protein format | Scientific Literature |